Photoredox-catalyzed C–H functionalization reactions

N Holmberg-Douglas, DA Nicewicz - Chemical reviews, 2021 - ACS Publications
The fields of C–H functionalization and photoredox catalysis have garnered enormous
interest and utility in the past several decades. Many different scientific disciplines have …

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds

R Cannalire, S Pelliccia, L Sancineto… - Chemical Society …, 2021 - pubs.rsc.org
The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool
to speed up the identification of structure–activity relationships (SARs) and to optimize …

[PDF][PDF] Photoinduced intermolecular hydrogen atom transfer reactions in organic synthesis

H Cao, X Tang, H Tang, Y Yuan, J Wu - Chem Catalysis, 2021 - cell.com
Hydrogen-atom transfer (HAT) provides straightforward methods to generate open-shell
radical intermediates from RH (R= C, Si, etc.) bonds and offers unique opportunities for …

Radical approaches to C–S bonds

Z Wu, DA Pratt - Nature Reviews Chemistry, 2023 - nature.com
Organosulfur functionalities are ubiquitous in nature, pharmaceuticals, agrochemicals,
materials and flavourants. Historically, these moieties were introduced almost exclusively …

Photocatalytic hydrogen atom transfer: the philosopher's stone for late-stage functionalization?

L Capaldo, LL Quadri, D Ravelli - Green Chemistry, 2020 - pubs.rsc.org
An overview about the potentialities of photocatalytic Hydrogen Atom Transfer (HAT) for the
Late-Stage Functionalization (LSF) of complex molecules is offered. The examined …

Aliphatic C–H Functionalization Using Pyridine N-Oxides as H-Atom Abstraction Agents

M Schlegel, S Qian, DA Nicewicz - ACS catalysis, 2022 - ACS Publications
The alkylation and heteroarylation of unactivated tertiary, secondary, and primary C (sp3)–H
bonds was achieved by employing an acridinium photoredox catalyst along with readily …

Merging carbonyl addition with photocatalysis

HM Huang, P Bellotti, F Glorius - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus The carbonyl group stands as a fundamental scaffold and plays a ubiquitous
role in synthetically important chemical reactions in both academic and industrial contexts …

Diastereoselective allylation of aldehydes by dual photoredox and chromium catalysis

JL Schwarz, F Schäfers, A Tlahuext-Aca… - Journal of the …, 2018 - ACS Publications
Herein, we report the redox-neutral allylation of aldehydes with readily available electron-
rich allyl (hetero-) arenes, β-alkyl styrenes and allyl-diarylamines. This process was enabled …

Photoinduced Site-Selective Functionalization of Aliphatic C–H Bonds by Pyridine N-oxide Based HAT Catalysts

B Wang, C Ascenzi Pettenuzzo, J Singh… - ACS …, 2022 - ACS Publications
Readily available and facilely tunable pyridine N-oxides have been developed as effective
photoinduced hydrogen-atom-transfer (HAT) catalysts for site-selective C–H …

Photogenerated acyl/alkoxycarbonyl/carbamoyl radicals for sustainable synthesis

C Raviola, S Protti, D Ravelli, M Fagnoni - Green Chemistry, 2019 - pubs.rsc.org
Acylation reactions are of crucial importance in synthesis since they provide access to
ketones or related derivatives. The well known acylations of aromatics (the Friedel–Crafts …