Epilepsy is one of the most common neurological disorders characterized by recurrent
seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N …

Homocysteine is a non-proteinogenic sulfhydryl-containing amino acid derived from
methionine and is a homologue of cysteine. The concentration of homocysteine is regulated …

Cardiotonic steroids (CTS) are a group of compounds existing in animals and plants. CTS
are commonly referred to cardiac glycosides (CGs) which are composed of sugar residues …

In recent years, enough evidence has accumulated to assert that cardiotonic steroids, Na+,
K+-ATPase ligands, play an integral role in the physiological and pathophysiological …

Na/K-ATPase maintains transmembrane ionic gradients and acts as a signal transducer
when bound to endogenous cardiotonic steroids. At subnanomolar concentrations, ouabain …

While there is a link between homocysteine (Hcy), B12 and folic acid and
neurodegeneration, especially in disorders like Parkinson's and Alzheimer's diseases, its …

Homocysteine (HCY) molecule combines distinct pharmacological properties as an agonist
of N-methyl-d-aspartate receptors (NMDARs) and a reducing agent. Whereas NMDAR …

A lipopolysaccharide (LPS)-induced neuroinflammation rat model was used to study the
effects of ouabain (OUA) at low concentrations, which can interact with the Na, K-ATPase …

Objective Seizures are a common clinical presentation in patients with glioma and
substantially impact patients' quality of life. Hyperhomocysteinemia is defined as abnormally …

Neonatal jaundice is a common symptom that occurs in neonates during the first month of
their life and is generally divided into physiological and pathological subtypes. In serious …