The interplay of immunology and cachexia in infection and cancer

H Baazim, L Antonio-Herrera… - Nature Reviews …, 2022 - nature.com
Diverse inflammatory diseases, infections and malignancies are associated with wasting
syndromes. In many of these conditions, the standards for diagnosis and treatment are …

Cancer cachexia: its mechanism and clinical significance

H Nishikawa, M Goto, S Fukunishi, A Asai… - International journal of …, 2021 - mdpi.com
The term “cachexia” is derived from the Greek words kakos (bad) and hexis (habit).
Cachexia is a malnutrition associated with chronic diseases such as cancer, chronic heart …

ESPEN guidelines on nutrition in cancer patients

J Arends, P Bachmann, V Baracos, N Barthelemy… - Clinical nutrition, 2017 - Elsevier
Cancers are among the leading causes of morbidity and mortality worldwide, and the
number of new cases is expected to rise significantly over the next decades. At the same …

Management of cancer cachexia: ASCO guideline

EJ Roeland, K Bohlke, VE Baracos, E Bruera… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based guidance on the clinical management of cancer
cachexia in adult patients with advanced cancer. METHODS A systematic review of the …

Cancer cachexia: Diagnosis, assessment, and treatment

M Sadeghi, M Keshavarz-Fathi, V Baracos… - Critical reviews in …, 2018 - Elsevier
Cancer cachexia is a multi-factorial syndrome, which negatively affects quality of life,
responsiveness to chemotherapy, and survival in advanced cancer patients. Our …

Cancer-induced muscle wasting: latest findings in prevention and treatment

Z Aversa, P Costelli… - Therapeutic advances in …, 2017 - journals.sagepub.com
Cancer cachexia is a severe and disabling clinical condition that frequently accompanies
the development of many types of cancer. Muscle wasting is the hallmark of cancer cachexia …

Cancer cachexia and related metabolic dysfunction

GWP Fonseca, J Farkas, E Dora… - International journal of …, 2020 - mdpi.com
Cancer cachexia is a complex multifactorial syndrome marked by a continuous depletion of
skeletal muscle mass associated, in some cases, with a reduction in fat mass. It is …

Pharmacological management of cachexia in adult cancer patients: a systematic review of clinical trials

SM Advani, PG Advani, HM VonVille, SH Jafri - BMC cancer, 2018 - Springer
Background Cachexia is a multisystem syndrome characterized by weight loss, anorexia,
loss of muscle mass, systemic inflammation, insulin resistance, and functional decline …

Nutritional considerations for head and neck cancer patients: a review of the literature

A Alshadwi, M Nadershah, ER Carlson… - Journal of Oral and …, 2013 - Elsevier
Purpose Approximately 35% to 60% of all patients with head and neck cancer are
malnourished at the time of their diagnosis because of tumor burden and obstruction of …

Espindolol for the treatment and prevention of cachexia in patients with stage III/IV non‐small cell lung cancer or colorectal cancer: a randomized, double‐blind …

AJ Stewart Coats, GF Ho, K Prabhash… - Journal of cachexia …, 2016 - Wiley Online Library
Background Cancer cachexia is a major cause of morbidity and mortality with no widely
approved treatment. Methods The ACT‐ONE trial is a randomized, double‐blind, parallel …