Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment

C Bertoncini-Silva, A Vlad, R Ricciarelli… - Antioxidants, 2024 - mdpi.com
Curcumin, a natural polyphenolic component from Curcuma longa roots, is the main
bioactive component of turmeric spice and has gained increasing interest due to its …

[HTML][HTML] Potential Protective Effects of Pungent Flavor Components in Neurodegenerative Diseases

F Guo, X Qin, J Mao, Y Xu, J **e - Molecules, 2024 - mdpi.com
Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
and Huntington's disease (HD) have become a major global health burden, but the detailed …

Ethosomes for curcumin and piperine cutaneous delivery to prevent environmental-stressor-induced skin damage

F Ferrara, A Bondi, W Pula, C Contado, A Baldisserotto… - Antioxidants, 2024 - mdpi.com
Diesel particulate matter is one of the most dangerous environmental stressors affecting
human health. Many plant-derived compounds with antioxidant and anti-inflammatory …

Investigating Bioavailability of Curcumin and Piperine Combination in Comparison to Turmeric Rhizomes: An in vitro Study

VL Pratti, M Thomas, R Bhoite… - Journal of Experimental …, 2024 - Taylor & Francis
Purpose To assess the permeability of the test item (a combination of curcumin and
piperine) and a reference item (dried and crushed turmeric rhizomes) using a combination of …

The assessment of pharmacokinetics and neuroprotective effect of berberine hydrochloride-embedded albumin nanoparticles via various administration routes …

HG Attia, ME Elmataeeshy, M Aleraky… - Journal of …, 2024 - Taylor & Francis
The current study aimed to evaluate the pharmacokinetics and neuroprotective effect of well-
characterised berberine-bovine serum albumin (BBR-BSA) nanoparticles. BBR-BSA …

[HTML][HTML] Evaluating Various Lactose Types as Solid Carriers for Improving Curcumin Solubility in Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDSs) for …

P Teerapipattanapong, P Jaikon, N Ningsanonda… - Sci, 2024 - mdpi.com
Curcumin, a bioactive compound derived from turmeric, possesses numerous
pharmaceutical properties; however, its poor aqueous solubility and permeability result in …

Formulation and optimization of fisetin nanoemulsion for the treatment of Alzheimer's disease in rats: Pharmacokinetic and pharmacodynamic assessment

S Vishwas, R Kumar, A Awasthi, L Corrie… - Journal of Drug Delivery …, 2024 - Elsevier
Fiestin (FS) is a polyphenolic flavonoid that possesses various neuroprotective effects by
attenuating the levels of AChE enzyme, accumulated amyloid β, free radicals and …

Phytosomes: A Cutting-Edge Platform for Phytochemicals Delivery by Enhancing Bioavailability

S Kumbhar, V Jagdale, M Bhatia - Jordan Journal of …, 2024 - jjournals.ju.edu.jo
The word" Phyto" signifies plant, while" some" is for cell. This innovative patented technology
involves combining plant extracts or hydrophilic phytoconstituents with phospholipids to …

Promising Strategies to Reduce the SARS-CoV-2 Amyloid Deposition in the Brain and Prevent COVID-19-Exacerbated Dementia and Alzheimer's Disease

N Navolokin, V Adushkina, D Zlatogorskaya… - Pharmaceuticals, 2024 - mdpi.com
The COVID-19 pandemic, caused by infection with the SARS-CoV-2 virus, is associated with
cognitive impairment and Alzheimer's disease (AD) progression. Once it enters the brain, the …

Phytocompounds and lipid-based drug delivery system for neurodegenerative diseases

C Ozay, M Karpuz - Asian Pacific Journal of Tropical Biomedicine, 2024 - journals.lww.com
Across the annals of time, organic molecules sourced from nature have found innumerable
uses within the realms of healthcare, pharmaceuticals, and the study of living organisms …