Sex differences in immune responses: Hormonal effects, antagonistic selection, and evolutionary consequences

J Roved, H Westerdahl, D Hasselquist - Hormones and behavior, 2017 - Elsevier
Males and females differ in both parasite load and the strength of immune responses and
these effects have been verified in humans and other vertebrates. Sex hormones act as …

How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings

LG Spurgin, DS Richardson - Proceedings of the …, 2010 - royalsocietypublishing.org
Major histocompatibility complex (MHC) genes have been put forward as a model for
studying how genetic diversity is maintained in wild populations. Pathogen-mediated …

Plasticity and robustness in development and evolution

P Bateson, P Gluckman - International Journal of Epidemiology, 2012 - academic.oup.com
Biology presents many wonders, but one of the most remarkable is how a complex
multicellular organism grows from a single cell. Until recently, the processes involved …

[BUCH][B] Reproductive biology of teleost fishes

RJ Wootton, C Smith - 2014 - books.google.com
Reproductive Biology of Teleost Fishes is the first integrated review of the reproductive
biology of the bony fishes, which are the most species-rich and diversified group of …

Evolution of the immune system influences speciation rates in teleost fishes

M Malmstrøm, M Matschiner, OK Tørresen, B Star… - Nature Genetics, 2016 - nature.com
Teleost fishes constitute the most species-rich vertebrate clade and exhibit extensive genetic
and phenotypic variation, including diverse immune defense strategies. The genomic basis …

Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations

C Eizaguirre, TL Lenz, M Kalbe, M Milinski - Nature communications, 2012 - nature.com
The genes of the major histocompatibility complex are the most polymorphic genes in
vertebrates, with more than 1,000 alleles described in human populations. How this …

Major H istocompatibility C omplex class II b polymorphism influences gut microbiota composition and diversity

DI Bolnick, LK Snowberg, JG Caporaso… - Molecular …, 2014 - Wiley Online Library
Animals harbour diverse communities of symbiotic bacteria, which differ dramatically among
host individuals. This heterogeneity poses an immunological challenge: distinguishing …

How domestication alters fish phenotypes

S Milla, A Pasquet, L El Mohajer… - Reviews in …, 2021 - Wiley Online Library
Domestication can be defined as the adaptation of an animal to the human environment and
its constraints. Accumulating evidence strongly indicates that domestication plays essential …

MHC heterozygosity limits T cell receptor variability in CD4 T cells

AJ Brown, J White, L Shaw, J Gross, A Slabodkin… - Science …, 2024 - science.org
αβ T cell receptor (TCR) V (D) J genes code for billions of TCR combinations. However, only
some appear on peripheral T cells in any individual because, to mature, thymocytes must …

Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field

C Eizaguirre, TL Lenz, M Kalbe, M Milinski - Ecology letters, 2012 - Wiley Online Library
Although crucial for the understanding of adaptive evolution, genetically resolved examples
of local adaptation are rare. To maximize survival and reproduction in their local …