[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
Theranostic imaging and multimodal photodynamic therapy and immunotherapy using the mTOR signaling pathway
H Zhou, D Tang, Y Yu, L Zhang, B Wang… - Nature …, 2023 - nature.com
Tumor metastases are considered the leading cause of cancer-associated deaths. While
clinically applied drugs have demonstrated to efficiently remove the primary tumor …
clinically applied drugs have demonstrated to efficiently remove the primary tumor …
A nanoencapsulated Ir (III)-phthalocyanine conjugate as a promising photodynamic therapy anticancer agent
J Bonelli, E Ortega-Forte, G Vigueras… - … applied materials & …, 2024 - ACS Publications
Despite the potential of photodynamic therapy (PDT) in cancer treatment, the development
of efficient and photostable photosensitizing molecules that operate at long wavelengths of …
of efficient and photostable photosensitizing molecules that operate at long wavelengths of …
Potent anticancer activity of a novel iridium metallodrug via oncosis
E Ortega-Forte, S Hernández-García… - Cellular and Molecular …, 2022 - Springer
Oncosis (from Greek ónkos, meaning “swelling”) is a non-apoptotic cell death process
related to energy depletion. In contrast to apoptosis, which is the main form of cell death …
related to energy depletion. In contrast to apoptosis, which is the main form of cell death …
Improving photodynamic therapy anticancer activity of a mitochondria-targeted coumarin photosensitizer using a polyurethane–polyurea hybrid nanocarrier
J Bonelli, E Ortega-Forte, A Rovira, M Bosch… - …, 2022 - ACS Publications
Integration of photosensitizers (PSs) within nanoscale delivery systems offers great potential
for overcoming some of the “Achiles' heels” of photodynamic therapy (PDT). Herein, we have …
for overcoming some of the “Achiles' heels” of photodynamic therapy (PDT). Herein, we have …
Mitochondria-targeted iridium (III) complexes encapsulated in liposome induce cell death through ferroptosis and gasdermin-mediated pyroptosis
C Huang, Y Yuan, G Li, S Tian, H Hu, J Chen… - European Journal of …, 2024 - Elsevier
This paper unveils a novel perspective on synthesis and characterization of the ligand 5-
bromo-2-amino-2'-(phenyl-1H-imidazo [4, 5-f][1, 10] phenanthroline)(BAPIP), and its iridium …
bromo-2-amino-2'-(phenyl-1H-imidazo [4, 5-f][1, 10] phenanthroline)(BAPIP), and its iridium …
Towards Selective Delivery of a Ruthenium (II) Polypyridyl Complex‐Containing Bombesin Conjugate into Cancer Cells
MJSA Silva, R Vinck, Y Wang, B Saubaméa… - …, 2023 - Wiley Online Library
An increasing number of novel Ru (II) polypyridyl complexes have been successfully applied
as photosensitizers (PSs) for photodynamic therapy (PDT). Despite recent advances in …
as photosensitizers (PSs) for photodynamic therapy (PDT). Despite recent advances in …
Targeted liposomes encapsulated iridium (III) compound greatly enhance anticancer efficacy and induce cell death via ferroptosis on HepG2 cells
J Chen, W Li, G Li, X Liu, C Huang, H Nie… - European Journal of …, 2024 - Elsevier
In this study, ligands 2-phenyl-1H-imidazo [4, 5-f][1, 10] phenanthroline (PIP), 2-(2-
nitrophenyl)-1H-imidazo [4, 5-f][1, 10] phenanthroline (NPIP), 2-(2-nitronaphthalen-1-yl)-1H …
nitrophenyl)-1H-imidazo [4, 5-f][1, 10] phenanthroline (NPIP), 2-(2-nitronaphthalen-1-yl)-1H …
[HTML][HTML] Insights into molecular mechanisms of metallodrugs using metallomic studies
S La Manna, D Marasco - Inorganica Chimica Acta, 2024 - Elsevier
Metal ions are the center of an important class of therapeutics, ie metallodrugs for their
unique coordination geometries and redox states. Many cellular functions depend on the …
unique coordination geometries and redox states. Many cellular functions depend on the …
Systematic study on interfacial polymerization mechanism of toluene diisocyanate and water for the preparation of polyurea microspheres
Polyureas (PU) are important materials in wide range of applications from protective
coatings and catalyst supports to biomaterials for drug release and hydrogels. However, it …
coatings and catalyst supports to biomaterials for drug release and hydrogels. However, it …