Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Activation of an aberrant glycosylation pathway in cancer cells can lead to expression of the
onco-foetal sialyl-Tn (sTn) antigen. STn is a truncated O-glycan containing a sialic acid α-2 …

Core fucosylation and O-GlcNAcylation are the two most famous protein glycosylation
modifications that regulate diverse physiological and pathological processes in living …

Carbohydrates are abundantly expressed on the surface of both eukaryotic and prokaryotic
cells, often as post translational modifications of proteins. Glycoproteins are recognized by …

Shark is a cartilaginous fish that produces new antigen receptor (IgNAR) antibodies. This
antibody is identified with a similar human heavy chain but dissimilar sequences. The …

This review highlights the recent development in the use of carriers of increasing simplicities
and versatile chemical ligation processes leading to synthetic vaccine candidates against …

Abstract Esophageal (OC), gastric (GC) and colorectal (CRC) cancers are amongst the
digestive track tumors with higher incidence and mortality due to significant molecular …

The mechanisms involved in immune responses to cancer have been extensively studied for
several decades, and considerable attention has been paid to harnessing the immune …

Alterations in glycosylation cause the emergence of tumor-associated carbohydrate
antigens (TACAs) during tumorigenesis. Truncation of O-glycans reveals the Thomsen …

There is an urgent need to develop new tumor biomarkers for early cancer detection, but the
variability of tumor-derived antigens has been a limitation. Here we demonstrate a novel anti …