Conflicting evidence exists concerning the effects of nutrient intake in osteoarthritis (OA). A
systematic literature review and meta-analysis were performed using PubMed, EMBASE …

Osteoarthritis (OA) is a disease which results in degeneration of cartilage within joints and
affects approximately 13.6% of adults over 20 years of age in Canada and the United States …

The burden of osteoarthritis (OA) is rapidly increasing with population aging, but there are
still no approved disease-modifying drugs available. Accumulating evidence has shown that …

Osteoarthritis (OA) is a highly prevalent condition worldwide associated with pain,
progressive disability, reduced participation in social activities, and impaired quality of life …

Objective Osteoarthritis (OA) displays features of systemic and local inflammation,
suggesting that DMARDs used in rheumatoid arthritis could potentially also be effective in …

Objective Colchicine, an approved treatment for gout, has been trialed in many diseases
including osteoarthritis (OA) due to its anti-inflammatory effects. However, its efficacy and …

Hydroxychloroquine (HCQ) is an antimalarial drug that has historically been used to treat
and prevent malaria. However, its mechanism of action has not yet been fully elucidated …

In recent years, researchers have examined the use of polyunsaturated fatty acids (PUFA) or
a low omega-6/3 ratio to protect the knee joint. The current study is based on genome-wide …

Osteoarthritis (OA) is a common joint disorder for which there is no cure. Current treatments
are suboptimal. Exercise is a core treatment for knee OA, with muscle strengthening …

Knee osteoarthritis (KOA) is a progressive joint disease and a leading source of chronic pain
and disability. OA-bone marrow lesions (BMLs) are a recognised aetiopathological feature …