The role of saliva in tick feeding

IMB Francischetti, A Sa-Nunes, BJ Mans… - … in bioscience: a …, 2009 - pmc.ncbi.nlm.nih.gov
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …

Tick-borne viruses and biological processes at the tick-host-virus interface

M Kazimírová, S Thangamani, P Bartíková… - Frontiers in cellular …, 2017 - frontiersin.org
Ticks are efficient vectors of arboviruses, although less than 10% of tick species are known
to be virus vectors. Most tick-borne viruses (TBV) are RNA viruses some of which cause …

The immunomodulatory factors of arthropod saliva and the potential for these factors to serve as vaccine targets to prevent pathogen transmission

RG Titus, JV Bishop, JS Mejia - Parasite immunology, 2006 - Wiley Online Library
In general, attempts to develop vaccines for pathogens transmitted by arthropods have met
with little or no success. It has been widely observed that the saliva of arthropods that …

Platelet-derived chemokines: pathophysiology and therapeutic aspects

HD Flad, E Brandt - Cellular and Molecular Life Sciences, 2010 - Springer
The identification of chemokines in blood platelets has strengthened our view of these cells
as participants in immune host defense. Platelet chemokines representing prestored and …

Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus

A Frauenschuh, CA Power, M Deruaz… - Journal of Biological …, 2007 - jbc.org
Ticks are blood-feeding parasites that secrete a number of immuno-modulatory factors to
evade the host immune response. Saliva isolated from different species of ticks has recently …

Saliva of the Yellow Fever mosquito, Aedes aegypti, modulates murine lymphocyte function

HA Wasserman, S Singh… - Parasite immunology, 2004 - Wiley Online Library
Saliva of many vector arthropods contains factors that inhibit haemostatic responses in their
vertebrate hosts. Less is known about the effect of vector saliva on host immune responses …

Manipulation of host cytokine network by ticks: a potential gateway for pathogen transmission

V Hajnicka, I Vančová, P Kocakova, M Slovak… - Parasitology, 2005 - cambridge.org
Ticks are obligatory blood-feeding arthropods that secrete various immunomodulatory
molecules to antagonize host inflammatory and immune responses. Cytokines play an …

Evasins: tick salivary proteins that inhibit mammalian chemokines

RP Bhusal, JRO Eaton, ST Chowdhury… - Trends in biochemical …, 2020 - cell.com
Ticks are hematophagous arachnids that parasitize mammals and other hosts, feeding on
their blood. Ticks secrete numerous salivary factors that enhance host blood flow or …

Multi-faceted strategies to combat disease by interference with the chemokine system

Z Johnson, M Schwarz, CA Power, TNC Wells… - TRENDS in …, 2005 - cell.com
Inappropriate cell recruitment is a hallmark of all autoimmune, allergic and inflammatory
diseases. The prevention of inflammation by interfering with cellular recruitment through the …

[PDF][PDF] Immunomodulators in tick saliva and their benefits

I Štibrániová, M Lahová, P Bartíková - Acta Virol, 2013 - frontierspartnerships.org
Ticks are significant bloodsucking ectoparasites. Apart from causing blood loss and host
skin damage, ticks are important vectors of tick-borne pathogens that cause disease in …