Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Contact lenses as ophthalmic drug delivery systems: a review

P Franco, I De Marco - Polymers, 2021 - mdpi.com
Ophthalmic drugs used for the treatment of various ocular diseases are commonly
administered by eye drops. However, due to anatomical and physiological factors, there is a …

Review of approaches for increasing ophthalmic bioavailability for eye drop formulations

OL Lanier, MG Manfre, C Bailey, Z Liu, Z Sparks… - Aaps Pharmscitech, 2021 - Springer
Ophthalmic diseases represent a significant problem as over 2 billion people worldwide
suffer from vison impairment and blindness. Eye drops account for around 90% of …

Cell-penetrating peptides for transmucosal delivery of proteins

J Wu, S Roesger, N Jones, CMJ Hu, SD Li - Journal of Controlled Release, 2024 - Elsevier
Enabling non-invasive delivery of proteins across the mucosal barriers promises improved
patient compliance and therapeutic efficacies. Cell-penetrating peptides (CPPs) are …

[HTML][HTML] Lipid nanoparticles for the posterior eye segment

L Bonilla, M Espina, P Severino, A Cano, M Ettcheto… - Pharmaceutics, 2021 - mdpi.com
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles,
Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for …

Challenges and strategies for ocular posterior diseases therapy via non-invasive advanced drug delivery

Q Qi, Y Wei, X Zhang, J Guan, S Mao - Journal of Controlled Release, 2023 - Elsevier
Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

Hyaluronic acid-based nanoparticles to deliver drugs to the ocular posterior segment

H Jiang, Z Xu - Drug Delivery, 2023 - Taylor & Francis
Ocular posterior segment diseases such as uveitis, X-linked juvenile retinoschisis, or age-
related macular degeneration usually result in progressive and irreversible vision loss …

Clinical significance of carnitine in the treatment of cancer: from traffic to the regulation

R Farahzadi, MS Hejazi, O Molavi… - Oxidative Medicine …, 2023 - Wiley Online Library
Metabolic reprogramming is a common hallmark of cancer cells. Cancer cells exhibit
metabolic flexibility to maintain high proliferation and survival rates. In other words …

Nanomicellar eye drops: a review of recent advances

V Paganini, P Chetoni, M Di Gangi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Research on nanotechnology in medicine has also involved the ocular field and
nanomicelles are among the applications developed. This approach is used to increase …

Flexible polymeric nanosized micelles for ophthalmic drug delivery: research progress in the last three years

Z Li, M Liu, L Ke, LJ Wang, C Wu, C Li, Z Li… - Nanoscale …, 2021 - pubs.rsc.org
The eye is a complex structure with a variety of anatomical barriers and clearance
mechanisms, so the provision of safe and effective ophthalmic drug delivery technology is a …