[HTML][HTML] Botulinum toxin intervention in cerebral palsy-induced spasticity management: projected and contradictory effects on skeletal muscles

CS Kaya Keles, F Ates - Toxins, 2022 - mdpi.com
Spasticity, following the neurological disorder of cerebral palsy (CP), describes a
pathological condition, the central feature of which is involuntary and prolonged muscle …

[HTML][HTML] Unraveling the threads of stability: a review of the neurophysiology of postural control in Parkinson's disease

JE Bath, DD Wang - Neurotherapeutics, 2024 - Elsevier
Postural instability is a detrimental and often treatment-refractory symptom of Parkinson's
disease. While many existing studies quantify the biomechanical deficits among various …

[HTML][HTML] Objective methods of muscle tone diagnosis and their application—a critical review

B Kopecka, D Ravnik, K Jelen, V Bittner - Sensors, 2023 - mdpi.com
“Muscle tone” is a clinically important and widely used term and palpation is a crucial skill for
its diagnosis. However, the term is defined rather vaguely, and palpation is not measurable …

Rigidity in Parkinson's disease: evidence from biomechanical and neurophysiological measures

F Asci, M Falletti, A Zampogna, M Patera, M Hallett… - Brain, 2023 - academic.oup.com
Although rigidity is a cardinal motor sign in patients with Parkinson's disease (PD), the
instrumental measurement of this clinical phenomenon is largely lacking, and its …

Reliability of MyotonPro in measuring the biomechanical properties of the quadriceps femoris muscle in people with different levels and types of motor preparation

R Trybulski, A Kużdżał, M Wilk, J Więckowski… - Frontiers in Sports and …, 2024 - frontiersin.org
The aim of this research was to evaluate the reliability of the measurements of
biomechanical parameters of the muscles of athletes representing different disciplines as …

Quantity and distribution of muscle spindles in animal and human muscles

Y Sun, C Fede, X Zhao, A Del Felice… - … Journal of Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
Muscle spindles have unique anatomical characteristics that can be directly affected by the
surrounding tissues under physiological and pathological conditions. Understanding their …

Effect of virtual running with exercise on functionality in pre-frail and frail elderly people: randomized clinical trial

S Mollà-Casanova, E Muñoz-Gómez… - Aging Clinical and …, 2023 - Springer
Background Virtual mirror therapies could increase the results of exercise, since the mirror
neuron system produces an activation of motor execution cortical areas by observing actions …

Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants

A Shipman, Y Gao, D Liu, S Sun, J Zang… - Journal of …, 2024 - jneurosci.org
Mutations in human VPS4A are associated with neurodevelopmental defects, including
motor delays and defective muscle tone. VPS4A encodes a AAA-ATPase required for …

Linking cortex and contraction—Integrating models along the corticomuscular pathway

L Haggie, L Schmid, O Röhrle, T Besier… - Frontiers in …, 2023 - frontiersin.org
Computational models of the neuromusculoskeletal system provide a deterministic
approach to investigate input-output relationships in the human motor system …

[HTML][HTML] Clinical measures for tone assessment in adults with central nervous system disorders—a sco** review in a rehabilitation context

L Pinho, S Silva, M Freitas, V Figueira, F Pinho… - Applied Sciences, 2024 - mdpi.com
Assessment of muscle tone in a clinical setting is important for the physiotherapist to better
analyse and establish appropriate treatments for CNS disorders. This study aims to review …