C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …

Exopolysaccharides (EPSs) synthesized by lactic acid bacteria (LAB) have implications for
host health and act as food ingredients. Due to the variability of LAB-EPS (lactic acid …

The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

Together with proteins and fats, carbohydrates are one of the macronutrients in the human
diet. Digestible carbohydrates, such as starch, starch-based products, sucrose, lactose …

The gastrointestinal tract (GIT) is colonized by a broad spectrum of microorganism, of which
bacteria are especially recognized for the health effects they exert. However insight in the …

Pathogen recognition by C-type lectin receptors (CLRs) expressed by dendritic cells is
important not only for antigen presentation, but also for the induction of appropriate adaptive …

Toll-like receptors (TLRs) sense invading microbial pathogens and play crucial roles in the
activation of innate and adaptive immunity. However, excessive TLR activation can disrupt …

Highlights•Sugar-binding C-type carbohydrate-recognition domains fall in five structural
groups.•Structures for many of these domains, covering all of the groups, have been …

Myeloid cells are key drivers of physiological responses to pathogen invasion or tissue
damage. Members of the C-type lectin receptor (CLR) family stand out among the …

C-type lectin receptors (CLRs) are important pattern recognition receptors involved in
recognition and induction of adaptive immunity to pathogens. Certain CLRs play an …