Abstract The Iberian Margin is a sensitive area to track high and low latitude processes, and
is a key location to understand major past climatic and oceanographic changes. Here we …

During the Pleistocene, long-term trends in global climate were controlled by orbital cycles
leading to high amplitude glacial-interglacial variability. The history of Amazonian vegetation …

Marked by a progressive increase in the amplitude of climate oscillations, an evolving
waveform, and a shift towards a quasi-100 ky frequency, the Early–Middle Pleistocene …

Climate variability over the past 800,000 years has long been described as being dominated
by~ 100-kyr glacial cycles, and researchers have debated whether these glacial cycles were …

Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent
need to promptly direct non-responder patients to alternative therapies. Infiltrating T …

Antarctic bottom water production is one of the most important components in oceanic
circulation, yet its long-term impact on Earth's climate remains poorly known. In this study …

The∼ 100 ky cyclicity of the late Pleistocene ice ages started during the mid-Pleistocene
transition (MPT), as ice sheets became larger and persisted for longer. The climate system …

The development of larger and longer lasting northern hemisphere ice sheets during the mid‐
Pleistocene Transition (MPT) coincided with global cooling. Here, we show that surface …

Large amplitude variations in atmospheric CO 2 were associated with glacial terminations of
the Late Pleistocene. Here we provide multiple lines of evidence suggesting that the∼ 20 …

The global ocean overturning circulation is a major means of distributing heat around the
Earth, and an important trigger or amplifier of climate change. This study presents a 1.5-Myr …