Ultrafast magic angle spinning solid-state NMR spectroscopy: Advances in methodology and applications

Y Nishiyama, G Hou, V Agarwal, Y Su… - Chemical …, 2022 - ACS Publications
Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …

Solid-state NMR: Methods for biological solids

S Ahlawat, KR Mote, NA Lakomek… - Chemical Reviews, 2022 - ACS Publications
In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Solid-state NMR spectroscopy

B Reif, SE Ashbrook, L Emsley, M Hong - Nature Reviews Methods …, 2021 - nature.com
Solid-state nuclear magnetic resonance (NMR) spectroscopy is an atomic-level method to
determine the chemical structure, 3D structure and dynamics of solids and semi-solids. This …

Atomic structure of the open SARS-CoV-2 E viroporin

J Medeiros-Silva, AJ Dregni, NH Somberg, P Duan… - Science …, 2023 - science.org
The envelope (E) protein of the SARS-CoV-2 virus forms cation-conducting channels in the
endoplasmic reticulum Golgi intermediate compartment (ERGIC) of infected cells. The …

[HTML][HTML] Solid-state NMR spectroscopy in pharmaceutical sciences

M Li, W Xu, Y Su - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials
in a non-disruptive and non-invasive manner. The obtained molecular properties at …

Oligomeric state and drug binding of the SARS-CoV-2 envelope protein are sensitive to the ectodomain

NH Somberg, I Sučec, J Medeiros-Silva… - Journal of the …, 2024 - ACS Publications
The envelope (E) protein of SARS-CoV-2 is the smallest of the three structural membrane
proteins of the virus. E mediates budding of the progeny virus in the endoplasmic reticulum …

From angstroms to nanometers: measuring interatomic distances by solid-state NMR

AA Shcherbakov, J Medeiros-Silva, N Tran… - Chemical …, 2021 - ACS Publications
Internuclear distances represent one of the main structural constraints in molecular structure
determination using solid-state NMR spectroscopy, complementing chemical shifts and …

Solid-state NMR of plant and fungal cell walls: a critical review

W Zhao, LD Fernando, A Kirui, F Deligey… - Solid state nuclear …, 2020 - Elsevier
The cell walls of plants and microbes are a central source for bio-renewable energy and the
major targets of antibiotics and antifungal agents. It is highly challenging to determine the …

Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer's β-Amyloid Fibrils Studied Using 19F Solid-State NMR

P Duan, KJ Chen, G Wijegunawardena… - Journal of the …, 2022 - ACS Publications
Amyloid imaging by positron emission tomography (PET) is an important method for
diagnosing neurodegenerative disorders such as Alzheimer's disease. Many 11C-and 18F …

Structure and dynamics of the drug-bound bacterial transporter EmrE in lipid bilayers

AA Shcherbakov, G Hisao, VS Mandala… - Nature …, 2021 - nature.com
The dimeric transporter, EmrE, effluxes polyaromatic cationic drugs in a proton-coupled
manner to confer multidrug resistance in bacteria. Although the protein is known to adopt an …