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The central role of cytochrome P450 in xenobiotic metabolism—a brief review on a fascinating enzyme family
F Esteves, J Rueff, M Kranendonk - Journal of xenobiotics, 2021 - mdpi.com
Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound
hemoproteins that are responsible for the metabolism of a wide variety of clinically …
hemoproteins that are responsible for the metabolism of a wide variety of clinically …
A review on anti-cancer properties of Quercetin in breast cancer
Breast cancer is one of the well-known malignant tumors among women. In spite of attempts
to classifying breast cancer according to its histological and molecular properties, it is almost …
to classifying breast cancer according to its histological and molecular properties, it is almost …
[HTML][HTML] AhR signaling pathways and regulatory functions
Animals and humans are exposed each day to a multitude of chemicals in the air, water and
food. They have developed a battery of enzymes and transporters that facilitate the …
food. They have developed a battery of enzymes and transporters that facilitate the …
Human cytochromes P450 in health and disease
There are 18 mammalian cytochrome P450 (CYP) families, which encode 57 genes in the
human genome. CYP2, CYP3 and CYP4 families contain far more genes than the other 15 …
human genome. CYP2, CYP3 and CYP4 families contain far more genes than the other 15 …
Heme-containing oxygenases
M Sono, MP Roach, ED Coulter, JH Dawson - Chemical reviews, 1996 - ACS Publications
Dioxygen (O2) serves two essential functions in aerobic life. It is both a terminal electron
acceptor and a biosynthetic reagent. It is this latter role for dioxygen that will be the focus of …
acceptor and a biosynthetic reagent. It is this latter role for dioxygen that will be the focus of …
The cytochrome p450 homepage
DR Nelson - Human genomics, 2009 - Springer
Abstract The Cytochrome P450 Homepage is a universal resource for nomenclature and
sequence information on cytochrome P450 (CYP) genes. The site has been in continuous …
sequence information on cytochrome P450 (CYP) genes. The site has been in continuous …
Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches
PD Noyes, KP Friedman, P Browne… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Extensive clinical and experimental research documents the potential for
chemical disruption of thyroid hormone (TH) signaling through multiple molecular targets …
chemical disruption of thyroid hormone (TH) signaling through multiple molecular targets …
[کتاب][B] Principles of ecotoxicology
CH Walker, RM Sibly, DB Peakall - 2005 - taylorfrancis.com
Presenting a multidisciplinary perspective in a concise format, Principles of Ecotoxicology,
Third Edition discusses the fundamental chemical and ecological nature of pollution …
Third Edition discusses the fundamental chemical and ecological nature of pollution …
Human ATP-binding cassette (ABC) transporter family
V Vasiliou, K Vasiliou, DW Nebert - Human genomics, 2009 - Springer
There exist four fundamentally different classes of membrane-bound transport proteins: ion
channels; transporters; aquaporins; and ATP-powered pumps. ATP-binding cassette (ABC) …
channels; transporters; aquaporins; and ATP-powered pumps. ATP-binding cassette (ABC) …
Clinical importance of the cytochromes P450
DW Nebert, DW Russell - The Lancet, 2002 - thelancet.com
The human cytochrome P450 (CYP) superfamily comprises 57 genes. These genes code for
enzymes that can have a role in: metabolism of drugs, foreign chemicals, arachidonic acid …
enzymes that can have a role in: metabolism of drugs, foreign chemicals, arachidonic acid …