Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020‏ - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

Detection and analysis of chiral molecules as disease biomarkers

Y Liu, Z Wu, DW Armstrong, H Wolosker… - Nature Reviews …, 2023‏ - nature.com
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

[HTML][HTML] Human exposure to neonicotinoids and the associated health risks: A review

D Zhang, S Lu - Environment international, 2022‏ - Elsevier
Neonicotinoids (NEOs) are a class of broad-spectrum insecticides dominant in the global
market. They were distributed extensively in the environment and occurred frequently in …

Chemical discovery in the era of metabolomics

M Sindelar, GJ Patti - Journal of the American Chemical Society, 2020‏ - ACS Publications
Untargeted metabolomics aims to quantify the complete set of metabolites within a biological
system, most commonly by liquid chromatography/mass spectrometry (LC/MS). Since nearly …

Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial

J Pezzatti, J Boccard, S Codesido, Y Gagnebin… - Analytica chimica …, 2020‏ - Elsevier
Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic
changes taking place in biological systems under different conditions. By its nature, this is a …

An epidemiological introduction to human metabolomic investigations

AD Joshi, A Rahnavard, P Kachroo, KM Mendez… - Trends in Endocrinology …, 2023‏ - cell.com
Metabolomics holds great promise for uncovering insights around biological processes
impacting disease in human epidemiological studies. Metabolites can be measured across …

Important considerations for sample collection in metabolomics studies with a special focus on applications to liver functions

L Smith, J Villaret-Cazadamont, SP Claus, C Canlet… - Metabolites, 2020‏ - mdpi.com
Metabolomics has found numerous applications in the study of liver metabolism in health
and disease. Metabolomics studies can be conducted in a variety of biological matrices …

Fingerprinting and profiling in metabolomics of biosamples

V Ghini, G Meoni, A Vignoli, F Di Cesare… - Progress in Nuclear …, 2023‏ - Elsevier
This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Plasma metabolites link dietary patterns to stroke risk

VM Bhave, Z Ament, A Patki, Y Gao… - Annals of …, 2023‏ - Wiley Online Library
Objective While dietary intake is linked to stroke risk, surrogate markers that could inform
personalized dietary interventions are lacking. We identified metabolites associated with diet …

Contribution and Effects of PM2.5-Bound Lead to the Cardiovascular Risk of Workers in a Non-Ferrous Metal Smelting Area Considering Chemical Speciation and …

X He, Q Zhao, X Chai, Y Song, X Li, X Lu… - Environmental …, 2023‏ - ACS Publications
Lead is known to have toxic effects on the cardiovascular system. Owing to its high
concentration, transmission range, and absorption efficiency in organisms, inhalation of fine …