Background Mycoplasma pneumoniae pneumonia (MPP), attributable to Mycoplasma
pneumoniae (MP), represents a predominant form of community-acquired pneumonia in …

Background In children, necrotizing pneumonia (NP) is an uncommon, severe complication
of pneumonia. It is characterized by destruction of the underlying lung parenchyma resulting …

Next-generation whole-genome sequencing is essential for high-resolution surveillance of
bacterial pathogens, for example, during outbreak investigations or for source tracking and …

Gram-negative bacteria release vesicular structures from their outer membrane, so called
outer membrane vesicles (OMVs). OMVs have a variety of functions such as waste disposal …

A key goal of pertussis control is to protect infants too young to be vaccinated, the age group
most vulnerable to this highly contagious respiratory infection. In the last decade, maternal …

Highlights•Immune protection against B. pertussis is multifactorial mediated by both humoral
and cellular responses.•Natural infection or vaccination with whole cell pertussis vaccine …

Pertussis has several notable consequences, causing economic burden, increased strain on
healthcare facilities, and reductions in quality of life. Recent years have seen a trend toward …

Pertussis is resurgent in some countries, particularly those in which children receive
acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic …

Introduction: Pertussis (whoo** cough) is a vaccine-preventable disease; however,
neither natural-nor vaccine-induced protection is life-long. Although generally not severe in …

Introduction Pertussis outbreaks have occurred in several industrialised countries using
acellular pertussis vaccines (ACVs) since the 1990s. High prevalence of pertactin (PRN) …