Tumor-associated macrophages: an effective player of the tumor microenvironment

U Basak, T Sarkar, S Mukherjee… - Frontiers in …, 2023 - frontiersin.org
Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Metastatic heterogeneity of breast cancer: Molecular mechanism and potential therapeutic targets

Y Liang, H Zhang, X Song, Q Yang - Seminars in cancer biology, 2020 - Elsevier
Breast cancer is one of the most common malignancies among women throughout the world
and is the major cause of most cancer-related deaths. Several explanations account for the …

Chemotherapy-induced complement signaling modulates immunosuppression and metastatic relapse in breast cancer

L Monteran, N Ershaid, H Doron, Y Zait… - Nature …, 2022 - nature.com
Mortality from breast cancer is almost exclusively a result of tumor metastasis and resistance
to therapy and therefore understanding the underlying mechanisms is an urgent challenge …

[HTML][HTML] Anticancer activities of TCM and their active components against tumor metastasis

K Wang, Q Chen, Y Shao, S Yin, C Liu, Y Liu… - Biomedicine & …, 2021 - Elsevier
Abstract Traditional Chinese Medicine (TCM) has the characteristics of multiple targets,
slight side effects and good therapeutic effects. Good anti-tumor effects are shown by …

Spatial and temporal map** of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary

I Yofe, T Shami, N Cohen, T Landsberger… - Cancer …, 2023 - aacrjournals.org
Cancer mortality primarily stems from metastatic recurrence, emphasizing the urgent need
for develo** effective metastasis-targeted immunotherapies. To better understand the …

Molecular mechanisms of breast cancer metastasis to the lung: clinical and experimental perspectives

B Medeiros, AL Allan - International journal of molecular sciences, 2019 - mdpi.com
Breast cancer is the most commonly diagnosed cancer in women worldwide, and> 90% of
breast cancer-related deaths are associated with metastasis. Breast cancer spreads …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

LncRNAs in breast cancer: a link to future approaches

N Sideris, P Dama, S Bayraktar, T Stiff… - Cancer Gene …, 2022 - nature.com
Breast cancer affects millions of women each year. Despite recent advances in targeted
treatments breast cancer remains a significant threat to women's health. In recent years the …

Targeting hypoxic tumors with hybrid nanobullets for oxygen-independent synergistic photothermal and thermodynamic therapy

D Gao, T Chen, S Chen, X Ren, Y Han, Y Li, Y Wang… - Nano-micro letters, 2021 - Springer
Hypoxia is a feature of solid tumors and it hinders the therapeutic efficacy of oxygen-
dependent cancer treatment. Herein, we have developed all-organic oxygen-independent …

Functional immune cell‐derived exosomes engineered for the trilogy of radiotherapy sensitization

X Ma, M Yao, Y Gao, Y Yue, Y Li, T Zhang… - Advanced …, 2022 - Wiley Online Library
The limited efficacy of radiotherapy leads to radio‐resistance and high rates of tumor
recurrence and metastasis, which is caused by tumor hypoxia, rapid DNA damage repair …