[HTML][HTML] Pharmacogenomics of Dementia: Personalizing the treatment of cognitive and neuropsychiatric symptoms

B Vuic, T Milos, L Tudor, M Nikolac Perkovic… - Genes, 2023 - mdpi.com
Dementia is a syndrome of global and progressive deterioration of cognitive skills,
especially memory, learning, abstract thinking, and orientation, usually affecting the elderly …

Paraoxonase 1 activity in patients with Alzheimer disease: Systematic review and meta-analysis

M Zuin, V Rosta, A Trentini, C Bosi, G Zuliani… - Chemico-Biological …, 2023 - Elsevier
Cumulating evidence links environmental toxicants, such as organophosphate (OP)
pesticides, to the pathogenesis of Alzheimer's disease (AD). The calcium-dependent …

[HTML][HTML] PON1 and PON3 in Alzheimer's Disease: Similar Functions but Different Roles

A Trentini, V Rosta, R Riccetti, G Mola, R Galletti… - Antioxidants, 2024 - mdpi.com
Paraoxonase 1 (PON1) and Paraoxonase 3 (PON3) are enzymes located on the surface of
high-density lipoprotein (HDL) and share similar antioxidant properties, possibly modulated …

[HTML][HTML] Paraoxonase I Activity and Its Relationship with Nutrition in Amyotrophic Lateral Sclerosis

B Proaño, M Benlloch, S Sancho-Castillo, J Privado… - Antioxidants, 2024 - mdpi.com
Background: Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor
neuron degeneration, with oxidative stress playing a key role. Paraoxonase 1 (PON1) is an …

Plasma biomarkers in patients with age-related sarcopenia: a proteomic exploration and experimental validation

Q Lin, K Li, L Li, L Guan, Y Zeng, D Cai, J Zhou… - Aging Clinical and …, 2025 - Springer
Background Various biomarkers associated with sarcopenia have been identified. However,
there is a scarcity of studies exploring and validating biomarkers in individuals with age …

Changes in Paraoxonase, β-Glucosidase, and Carbonic Anhydrase Enzymes Related to Age and Scopolamine-Induced Memory Impairment in Rats

H Yildirim, E Aksöz, B Efe Daşkan, F Şen, M Çelebi - Applied Sciences, 2024 - mdpi.com
This study aimed to investigate the changes in Paraoxonase (PON), Carbonic Anhydrase
(CA), and β-glucosidase levels of different aged rats and scopolamine-induced memory …

The analysis of PON1 gene expression and rs662 polymorphism in Iranian patients suffering from cardiovascular diseases

L Mahya, E Moslemi, K Esfahani… - Momona Ethiopian Journal …, 2025 - ajol.info
In addition to lifestyle and diet, cardiovascular disease can be caused by genetic factors
related to heart function issues and the blood biochemical content. The PON1 gene encodes …

Enzyme Activity and Genetic Polymorphisms of Paraoxonase 1 in Patients With Type 2 Diabetes Mellitus: A Case-Control Study

E Kocyigit, MG Karadağ, M Akturk, A Varis - 2025 - researchsquare.com
Abstract Paraoxonase-1 (PON1) plays a role in the prevention of lipid peroxidation and has
been linked to type 2 diabetes mellitus, which is characterised by elevated oxidative stress …

Assessment of Serum Level of Paraoxonase-1 in Patients with Non-Segmental Vitiligo

MA Elnadi, AS Hasan, SR Ismail, AA Ahmed - Egyptian Journal of Hospital …, 2024 - ajol.info
Background: Vitiligo is a chronic progressive depigmented skin disorder, characterized by
extensive melanocytes destruction. The explanation for the skin problem remains unknown …

Changes in paraoxonase, β-glucosidase, and carbonic anhydrase enzymes related to age and scopolamine-induced memory impairment in rats

H Yıldırım, E Aksöz, BE Daşkan, F Şen, M Çelebi - 2024 - dspace.balikesir.edu.tr
This study aimed to investigate the changes in Paraoxonase (PON), Carbonic Anhydrase
(CA), and β-glucosidase levels of different aged rats and scopolamine-induced memory …