Call to action regarding the vascular‐bipolar link: a report from the Vascular Task Force of the International Society for Bipolar Disorders

BI Goldstein, BT Baune, DJ Bond, PH Chen… - Bipolar …, 2020 - Wiley Online Library
Objectives The association of bipolar disorder with early and excessive cardiovascular
disease was identified over a century ago. Nonetheless, the vascular‐bipolar link remains …

Does metabolic syndrome or its component factors alter the course of bipolar disorder? A systematic review

A Gimenez-Palomo, S Gomes-da-Costa, S Dodd… - Neuroscience & …, 2022 - Elsevier
Metabolic syndrome (MetS) and its component factors, obesity, hypertension, dyslipidaemia
and insulin resistance, have shown a bidirectional relationship with the prevalence and …

Neurococognitive and neuroimaging correlates of obesity and components of metabolic syndrome in bipolar disorder: a systematic review

E Bora, RS McIntyre, A Ozerdem - Psychological medicine, 2019 - cambridge.org
BackgroundIndividuals with bipolar disorder (BD) have a higher prevalence of obesity and
metabolic syndrome (MetS) compared with the general population. Obesity and MetS are …

Association between body mass index and subcortical brain volumes in bipolar disorders–ENIGMA study in 2735 individuals

SR McWhinney, C Abé, M Alda, F Benedetti… - Molecular …, 2021 - nature.com
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often
associated with neurostructural alterations. Yet, the effects of obesity on brain structure in BD …

Inflammation associated with volume reduction in the gray matter and hippocampus of older patients with bipolar disorder

SY Tsai, AG Gildengers, JL Hsu, KH Chung… - Journal of Affective …, 2019 - Elsevier
Background Bipolar disorder (BD) and aging appear to be associated with inflammatory
activation. Inflammatory processes might affect hippocampal function, neurogenesis, and …

Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants

SR McWhinney, C Abé, M Alda, F Benedetti… - Psychological …, 2023 - cambridge.org
Background: Obesity is highly prevalent and disabling, especially in individuals with severe
mental illness including bipolar disorders (BD). The brain is a target organ for both obesity …

The impact of body mass index on the clinical features of bipolar disorder: A STEP‐BD study

B Kadriu, ZD Deng, C Kraus, JN Johnston… - Bipolar …, 2024 - Wiley Online Library
Introduction The effects of body mass index (BMI) on the core symptoms of bipolar disorder
(BD) and its implications for disease trajectory are largely unexplored. Objective To examine …

Elevated lipids are associated with reduced regional brain structure in youth with bipolar disorder

KG Kennedy, AH Islam, A Grigorian… - Acta Psychiatrica …, 2021 - Wiley Online Library
Objective Abnormal blood lipid levels are common in bipolar disorder (BD) and correlate
with mood symptoms and neurocognition. However, studies have not examined the lipid …

Gray matter hypertrophy in primary insomnia: a surface-based morphometric study

S Yu, F Feng, Q Zhang, Z Shen, Z Wang, Y Hu… - Brain imaging and …, 2020 - Springer
Studies have explored brain structural abnormalities in patients with primary insomnia (PI).
However, most of them are based on volumetric measures, in a specific region of interest …

[HTML][HTML] Cerebral Blood Flow and Core Mood Symptoms in Youth Bipolar Disorder: Evidence for Region–Symptom Specificity

MK Dimick, S Toma, BJ MacIntosh, A Grigorian… - Journal of the American …, 2022 - Elsevier
Objective Building on prior findings in adults, this study investigated regional cerebral blood
flow (CBF) in relation to DSM-5 criterion A symptoms of depression and mania in youth with …