Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines

S Di Saverio, M Podda, B De Simone… - World journal of …, 2020 - Springer
Background and aims Acute appendicitis (AA) is among the most common causes of acute
abdominal pain. Diagnosis of AA is still challenging and some controversies on its …

WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections

M Sartelli, F Coccolini, Y Kluger, E Agastra… - World journal of …, 2021 - Springer
Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in hospitals worldwide. The cornerstones of …

Neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine serum

K Uriu, I Kimura, K Shirakawa… - … England Journal of …, 2021 - Mass Medical Soc
Neutralization of the SARS-CoV-2 Mu Variant The mu variant of SARS-CoV-2 was 10.6
times as resistant to neutralization by serum samples obtained from persons who had …

Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial

P Salminen, R Tuominen, H Paajanen, T Rautio… - Jama, 2018 - jamanetwork.com
Importance Short-term results support antibiotics as an alternative to surgery for treating
uncomplicated acute appendicitis, but long-term outcomes are not known. Objective To …

The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections

M Sartelli, A Chichom-Mefire, FM Labricciosa… - World Journal of …, 2017 - Springer
Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported
as major contributors to non-trauma deaths in the emergency departments worldwide. The …

Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children: a systematic review and meta-analysis

M Podda, C Gerardi, N Cillara, N Fearnhead… - Annals of …, 2019 - journals.lww.com
Objective: The aim of this meta-analysis was to summarize the current available evidence on
nonoperative management (NOM) with antibiotics for uncomplicated appendicitis, both in …

Diagnosis of uncomplicated and complicated appendicitis in adults

WJ Bom, JCG Scheijmans, P Salminen… - … journal of surgery, 2021 - journals.sagepub.com
Background: Diagnostic work-up of acute appendicitis remains challenging. While some
guidelines advise to use a risk stratification based on clinical parameters, others use …

Comparison of antibiotic therapy and appendectomy for acute uncomplicated appendicitis in children: a meta-analysis

L Huang, Y Yin, L Yang, C Wang, Y Li, Z Zhou - JAMA pediatrics, 2017 - jamanetwork.com
Importance Antibiotic therapy for acute uncomplicated appendicitis is effective in adult
patients, but its application in pediatric patients remains controversial. Objective To compare …

Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines

F Coccolini, M Sartelli, R Sawyer, K Rasa… - World journal of …, 2023 - Springer
Intra-abdominal infections (IAI) are among the most common global healthcare challenges
and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their …

Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

M Sartelli, F Catena, FM Abu-Zidan, L Ansaloni… - World journal of …, 2017 - Springer
This paper reports on the consensus conference on the management of intra-abdominal
infections (IAIs) which was held on July 23, 2016, in Dublin, Ireland, as a part of the annual …