MicroRNA and cancer–a brief overview

M Acunzo, G Romano, D Wernicke… - Advances in biological …, 2015 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - Elsevier
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

microRNAs in cancer management

YW Kong, D Ferland-McCollough, TJ Jackson… - The lancet …, 2012 - thelancet.com
Since the identification of microRNAs (miRNAs) in 1993, and the subsequent discovery of
their highly conserved nature in 2000, the amount of research into their function …

The role of miR‐21 in cancer

SR Pfeffer, CH Yang, LM Pfeffer - Drug development research, 2015 - Wiley Online Library
ABSTRACT Preclinical Research MicroRNAs (miRNAs) are small endogenous noncoding
RNAs that suppress gene expression at the post‐transcriptional level. In the past decade …

[HTML][HTML] Molecular mechanisms of cutaneous squamous cell carcinoma

ML Hedberg, CT Berry, AS Moshiri, Y **ang… - International Journal of …, 2022 - mdpi.com
Non-melanoma skin cancers are cutaneous malignancies representing the most common
form of cancer in the United States. They are comprised predominantly of basal cell …

Mechanisms that link the oncogenic epithelial–mesenchymal transition to suppression of anoikis

SM Frisch, M Schaller, B Cieply - Journal of cell science, 2013 - journals.biologists.com
The oncogenic epithelial–mesenchymal transition (EMT) contributes to tumor progression in
various context-dependent ways, including increased metastatic potential, expansion of …

Suppression of the epithelial–mesenchymal transition by Grainyhead-like-2

B Cieply, P Riley IV, PM Pifer, J Widmeyer… - Cancer …, 2012 - aacrjournals.org
Grainyhead genes are involved in wound healing and developmental neural tube closure. In
light of the high degree of similarity between the epithelial–mesenchymal transitions (EMT) …

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

N Mancuso, S Gayther, A Gusev, W Zheng… - Nature …, 2018 - nature.com
Although genome-wide association studies (GWAS) for prostate cancer (PrCa) have
identified more than 100 risk regions, most of the risk genes at these regions remain largely …

Epithelial–mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2

B Cieply, J Farris, J Denvir, HL Ford, SM Frisch - Cancer research, 2013 - aacrjournals.org
Epithelial–mesenchymal transition (EMT) in carcinoma cells enhances malignant
progression by promoting invasion and survival. EMT is induced by microenvironmental …

The role of microRNA-21 in the onset and progression of cancer

A Singh, AK Singh, R Giri, D Kumar… - Future Medicinal …, 2021 - Taylor & Francis
MicroRNAs (miRNAs), a class of small noncoding RNA, posttranscriptionally regulate the
expression of genes. Aberrant expression of miRNA is reported in various types of cancer …