[HTML][HTML] Bone/cartilage targeted hydrogel: Strategies and applications

H Zhang, S Wu, W Chen, Y Hu, Z Geng, J Su - Bioactive materials, 2023 - Elsevier
The skeletal system is responsible for weight-bearing, organ protection, and movement.
Bone diseases caused by trauma, infection, and aging can seriously affect a patient's quality …

Clay nanoparticles for regenerative medicine and biomaterial design: A review of clay bioactivity

M Mousa, ND Evans, ROC Oreffo, JI Dawson - Biomaterials, 2018 - Elsevier
Clay nanoparticles, composites and hydrogels are emerging as a new class of biomaterial
with exciting potential for tissue engineering and regenerative medicine applications. Clay …

Delivery across the blood-brain barrier: nanomedicine for glioblastoma multiforme

L Jena, E McErlean, H McCarthy - Drug delivery and translational research, 2020 - Springer
The malignant brain cancer, glioblastoma multiforme (GBM), is heterogeneous, infiltrative,
and associated with chemo-and radioresistance. Despite pharmacological advances …

Pore-forming bioinks to enable spatio-temporally defined gene delivery in bioprinted tissues

T Gonzalez-Fernandez, S Rathan, C Hobbs… - Journal of Controlled …, 2019 - Elsevier
The regeneration of complex tissues and organs remains a major clinical challenge. With a
view towards bioprinting such tissues, we developed a new class of pore-forming bioink to …

[HTML][HTML] Preparation and application of calcium phosphate nanocarriers in drug delivery

C Qiu, Y Wu, Q Guo, Q Shi, J Zhang, Y Meng, F **a… - Materials Today Bio, 2022 - Elsevier
Calcium phosphate nanoparticles represent promising materials for drug delivery because
of its favorable properties, including biocompatibility, biodegradability and strong affinity for …

[HTML][HTML] Octacalcium phosphate: Innovative vehicle for the local biologically active substance delivery in bone regeneration

I Kovrlija, J Locs, D Loca - Acta Biomaterialia, 2021 - Elsevier
Disadvantages of conventional drug delivery systems (DDS), such as systemic circulation,
interaction with physiochemical factors, reduced bioavailability, and insufficient drug …

Calcium phosphate nanoparticles-based systems for RNAi delivery: Applications in bone tissue regeneration

TJ Levingstone, S Herbaj, J Redmond, HO McCarthy… - Nanomaterials, 2020 - mdpi.com
Bone-related injury and disease constitute a significant global burden both socially and
economically. Current treatments have many limitations and thus the development of new …

Scaffold‐based microRNA therapies in regenerative medicine and cancer

CM Curtin, IM Castaño… - Advanced healthcare …, 2018 - Wiley Online Library
Abstract microRNA‐based therapies are an advantageous strategy with applications in both
regenerative medicine (RM) and cancer treatments. microRNAs (miRNAs) are an …

The use of bioactive peptides to modify materials for bone tissue repair

C Wang, Y Liu, Y Fan, X Li - Regenerative biomaterials, 2017 - academic.oup.com
It has been well recognized that the modification of biomaterials with appropriate bioactive
peptides could further enhance their functions. Especially, it has been shown that peptide …

Unravelling doped biphasic calcium phosphate: synthesis to application

S Basu, B Basu - ACS Applied Bio Materials, 2019 - ACS Publications
Among synthetic biomaterials, calcium phosphate (CaP)-based bioceramics, specifically
hydroxyapatite (HA) and tricalcium phosphate (TCP) as well as biphasic calcium phosphate …