Building and applying quantitative adverse outcome pathway models for chemical hazard and risk assessment

EJ Perkins, R Ashauer, L Burgoon… - Environmental …, 2019‏ - academic.oup.com
An important goal in toxicology is the development of new ways to increase the speed,
accuracy, and applicability of chemical hazard and risk assessment approaches. A …

Ecological models supporting environmental decision making: a strategy for the future

A Schmolke, P Thorbek, DL DeAngelis… - Trends in ecology & …, 2010‏ - cell.com
Ecological models are important for environmental decision support because they allow the
consequences of alternative policies and management scenarios to be explored. However …

[ספר][B] Fundamentals of ecotoxicology

MC Newman - 2009‏ - taylorfrancis.com
Each year ecotoxicological problems become increasingly complex and encompass
broader spatial and temporal scales. Our practical understanding must evolve accordingly to …

Towards better modelling and decision support: Documenting model development, testing, and analysis using TRACE

V Grimm, J Augusiak, A Focks, BM Frank, F Gabsi… - Ecological …, 2014‏ - Elsevier
The potential of ecological models for supporting environmental decision making is
increasingly acknowledged. However, it often remains unclear whether a model is realistic …

General unified threshold model of survival-a toxicokinetic-toxicodynamic framework for ecotoxicology

T Jager, C Albert, TG Preuss… - Environmental science & …, 2011‏ - ACS Publications
Toxicokinetic-toxicodynamic models (TKTD models) simulate the time-course of processes
leading to toxic effects on organisms. Even for an apparently simple endpoint as survival, a …

Merging validation and evaluation of ecological models to 'evaludation': A review of terminology and a practical approach

J Augusiak, PJ Van den Brink, V Grimm - Ecological Modelling, 2014‏ - Elsevier
Confusion about model validation is one of the main challenges in using ecological models
for decision support, such as the regulation of pesticides. Decision makers need to know …

Framework for traits‐based assessment in ecotoxicology

MN Rubach, R Ashauer, DB Buchwalter… - Integrated …, 2011‏ - academic.oup.com
A key challenge in ecotoxicology is to assess the potential risks of chemicals to the wide
range of species in the environment on the basis of laboratory toxicity data derived from a …

Potential application of population models in the European ecological risk assessment of chemicals II: Review of models and their potential to address environmental …

N Galic, U Hommen, JM Baveco… - Integrated …, 2010‏ - academic.oup.com
Whereas current chemical risk assessment (RA) schemes within the European Union (EU)
focus mainly on toxicity and bioaccumulation of chemicals in individual organisms, most …

The role of ecological models in linking ecological risk assessment to ecosystem services in agroecosystems

N Galic, A Schmolke, V Forbes, H Baveco… - Science of the Total …, 2012‏ - Elsevier
Agricultural practices are essential for sustaining the human population, but at the same time
they can directly disrupt ecosystem functioning. Ecological risk assessment (ERA) aims to …

Extrapolating ecotoxicological effects from individuals to populations: a generic approach based on Dynamic Energy Budget theory and individual-based modeling

BT Martin, T Jager, RM Nisbet, TG Preuss… - Ecotoxicology, 2013‏ - Springer
Individual-based models (IBMs) predict how dynamics at higher levels of biological
organization emerge from individual-level processes. This makes them a particularly useful …