Selected strategies to fight pathogenic bacteria

A Plotniece, A Sobolev, CT Supuran… - Journal of enzyme …, 2023 - Taylor & Francis
Natural products and analogues are a source of antibacterial drug discovery. Considering
drug resistance levels emerging for antibiotics, identification of bacterial metalloenzymes …

Bioactive compounds from the Zingiberaceae Family with known antioxidant activities for possible therapeutic uses

RN Alolga, F Wang, X Zhang, J Li, LSP Tran, X Yin - Antioxidants, 2022 - mdpi.com
The Zingiberaceae family is a rich source of diverse bioactive phytochemicals. It comprises
about 52 genera and 1300 species of aromatic flowering perennial herbs with characteristic …

No country for old antibiotics! Antimicrobial peptides (AMPs) as next-generation treatment for skin and soft tissue infection

M Răileanu, R Borlan, A Campu, L Janosi… - International Journal of …, 2023 - Elsevier
In recent years, the unprecedented rise of bacterial antibiotic resistance together with the
lack of adequate therapies have made the treatment of skin infections and chronic wounds …

Antibacterial drugs and cyclodextrin inclusion complexes: a patent review

AM Santos, C Carvalho Santana Júnior… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Bacterial antibiotic resistance occurs when bacteria mutate and escape the
effect of antibiotics, which makes the antibiotics no longer effective in treating infections …

SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria

EME Dokla, NS Abutaleb, SN Milik, EAEA Kandil… - European Journal of …, 2023 - Elsevier
Antibiotic-resistant bacteria represent a serious threat to modern medicine and human life.
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …

Functional Materials to Overcome Bacterial Barriers and Models to Advance Their Development

A Bali, MAM Kamal, G Mulla, B Loretz… - Advanced Functional …, 2023 - Wiley Online Library
With the emerging problem of antimicrobial resistance, the world is facing a slow but
dangerous pandemic. While the discovery of novel antibiotics is reaching a nearly …

Microfluidic Synthesis of Magnetite Nanoparticles for the Controlled Release of Antibiotics

C Chircov, IA Dumitru, BS Vasile, OC Oprea… - Pharmaceutics, 2023 - mdpi.com
Magnetite nanoparticles (MNPs) have been intensively studied for biomedical applications,
especially as drug delivery systems for the treatment of infections. Additionally, they are …

[HTML][HTML] Improved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier

J Werner, F Umstätter, T Hertlein, B Beijer… - … , Biology and Medicine, 2024 - Elsevier
Antibiotic resistance still represents a global health concern which diminishes the pool of
effective antibiotics. With the vancomycin derivative FU002, we recently reported a highly …

Colloidal Structure Dictates Antimicrobial Efficacy in LL‐37 Self‐Assemblies With Glycerol Monooleate

JDP Valentin, P Kadakia, LJ Varidel, MCA Stuart… - Small, 2024 - Wiley Online Library
The antimicrobial peptide LL‐37 is a promising alternative to conventional antibiotics to
combat bacteria in suspension and biofilms. Its self‐assembly with polar lipids is suggested …

Peptide-based materials that exploit metal coordination

GA Bassan, S Marchesan - International Journal of Molecular Sciences, 2022 - mdpi.com
Metal–ion coordination has been widely exploited to control the supramolecular behavior of
a variety of building blocks into functional materials. In particular, peptides offer great …