Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

The human blood-brain barrier (hBBB) is a highly specialized structure that regulates
passage across blood and central nervous system (CNS) compartments. Despite its critical …

Linking variants from genome-wide association studies (GWAS) to underlying mechanisms
of disease remains a challenge,–. For some diseases, a successful strategy has been to …

The high morbidity, mortality, and disability rates associated with cerebrovascular disease
(CeVD) pose a severe danger to human health. Gut bacteria significantly affect the onset …

Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in
disorders ranging from stroke, cancer, diabetic retinopathy, and Alzheimer's disease. The …

The glial environment influences neurological disease progression, yet much of our
knowledge still relies on preclinical animal studies, especially regarding astrocyte …

Key Points Cerebral Cavernous Malformations CCMs are found in approximately 0.5% of
the population and characteristically manifest with headache, seizure, or focal neurologic …

Silica nanoparticles have emerged as promising candidates in the field of nanomedicine
due to their remarkable versatility and customizable properties. However, concerns about …

Cavernous malformations (CMs) invading the central nervous system occur in~ 0.16–0.4%
of the general population, often resulting in hemorrhages and focal neurological deficits …