Elevated pro-inflammatory biomarkers and cytokines are associated with morbidity and
mortality in heart failure (HF). Preclinical and clinical studies have shown multiple …

The human heart has the least regenerative capabilities among tissues and organs, and
heart disease continues to be a leading cause of mortality in the industrialized world with …

Myocardial infarction (MI) leads to the mass death of cardiomyocytes accompanying with the
unfavorable alternation of microenvironment, a fibrosis scar deprived of electrical …

NRG1 (Neuregulin-1) is an effective cardiomyocyte proliferator, secreted and released by
endothelial vascular cells, and affects the cardiovascular system. It plays a major role in …

The regenerative capacity of an adult cardiac tissue is insufficient to repair the massive loss
of heart tissue, particularly cardiomyocytes (CMs), following ischemia or other catastrophic …

Self‐healing injectable hydrogel biomaterials uniquely enable precise therapeutic
deposition and deployment at specific bodily locations through versatile and minimally …

Myocardial Infarction (MI) is the most common cardiovascular disease. An average-sized MI
causes the loss of up to 1 billion cardiomyocytes and the adult heart lacks the capacity to …

Myocardial infarction causes cardiac tissue damage and the release of damage-associated
molecular patterns leads to activation of the immune system, production of inflammatory …

The mammalian hearts have the least regenerative capabilities among tissues and organs.
As such, heart regeneration has been and continues to be the ultimate goal in the treatment …

Cardiovascular diseases are the leading cause of death today and a significant public
health problem. Currently, there is no proper treatment for major cardiovascular diseases …