Impact of diabetes, obesity, and dyslipidemia on the risk of hepatocellular carcinoma in patients with chronic liver diseases

HS Shin, BG Jun, SW Yi - Clinical and molecular hepatology, 2022 - pmc.ncbi.nlm.nih.gov
Despite the increasing prevalence of metabolic disorders, the potential effects of metabolic
factors on hepatocellular carcinoma (HCC) development in individuals with chronic liver …

Statin use and risk of cirrhosis and related complications in patients with chronic liver diseases: a systematic review and meta-analysis

RG Kim, R Loomba, LJ Prokop, S Singh - Clinical gastroenterology and …, 2017 - Elsevier
Background & Aims Statins have been variably shown to decrease risk and complications of
chronic liver diseases (CLDs). We performed a systematic review and meta-analysis to …

Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017

AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Addition of simvastatin to standard therapy for the prevention of variceal rebleeding does not reduce rebleeding but increases survival in patients with cirrhosis

JG Abraldes, C Villanueva, C Aracil, J Turnes… - Gastroenterology, 2016 - Elsevier
Background & Aims The combination of β-blockers and band ligation is the standard
approach to prevent variceal rebleeding, but bleeding recurs and mortality is high. The lipid …

Statin use and reduced hepatocellular carcinoma risk in patients with nonalcoholic fatty liver disease

B Zou, MC Odden, MH Nguyen - Clinical Gastroenterology and Hepatology, 2023 - Elsevier
Background & Aims Recent evidence suggests potential clinical benefits of statin in cancer
chemoprevention and treatment. Nonalcoholic fatty liver disease (NAFLD) is expected to …

The short‐term incidence of hepatocellular carcinoma is not increased after hepatitis C treatment with direct‐acting antivirals: An ERCHIVES study

DK Li, Y Ren, DS Fierer, S Rutledge, OS Shaikh… - Hepatology, 2018 - journals.lww.com
Abstract β‐Catenin, the downstream effector of the Wnt signaling, plays important roles in
hepatic development, regeneration, and tumorigenesis. However, its role at hepatocyte …

Statins are associated with a decreased risk of decompensation and death in veterans with hepatitis C–related compensated cirrhosis

A Mohanty, JP Tate, G Garcia-Tsao - Gastroenterology, 2016 - Elsevier
Background & Aims Statins decrease portal pressure in patients with cirrhosis and increase
survival times of patients who have bled from varices. However, statins can be hepatotoxic. It …

[PDF][PDF] Atorvastatin and fluvastatin are associated with dose‐dependent reductions in cirrhosis and hepatocellular carcinoma, among patients with hepatitis C virus …

TG Simon, H Bonilla, P Yan, RT Chung, AA Butt - Hepatology, 2016 - Wiley Online Library
Statins are associated with delayed fibrosis progression and a reduced risk of hepatocellular
carcinoma (HCC) in chronic hepatitis C virus (HCV). Limited data exist regarding the most …

[HTML][HTML] Statin use decreases the incidence of hepatocellular carcinoma: an updated meta-analysis

A Facciorusso, MA Abd El Aziz, S Singh, S Pusceddu… - Cancers, 2020 - mdpi.com
Statins can decrease hepatocellular carcinoma (HCC) occurrence, but the magnitude and
the predictors of these effects remain unclear. This meta-analysis provides a pooled …

Use of statins in patients with chronic liver disease and cirrhosis: current views and prospects

JI Vargas, M Arrese, VH Shah, JP Arab - Current gastroenterology reports, 2017 - Springer
Purpose of review The purpose of this study is to analyze the current evidence regarding the
use of statins in patients with chronic liver disease and cirrhosis. Recent findings Chronic …