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EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?
Epithelial mesenchymal transition (EMT) and mesenchymal epithelial transition (MET) are
genetic determinants of cellular plasticity. These programs operate in physiological …
genetic determinants of cellular plasticity. These programs operate in physiological …
Tumor immune microenvironment during epithelial–mesenchymal transition
M Taki, K Abiko, M Ukita, R Murakami… - Clinical Cancer …, 2021 - aacrjournals.org
Epithelial–mesenchymal transition (EMT) has been shown to play a critical role in tumor
development from initiation to metastasis. EMT could be regarded as a continuum, with …
development from initiation to metastasis. EMT could be regarded as a continuum, with …
EMT factors and metabolic pathways in cancer
The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …
Crosstalk between peroxisome proliferator-activated receptor gamma and the canonical WNT/β-catenin pathway in chronic inflammation and oxidative stress during …
A Vallée, Y Lecarpentier - Frontiers in immunology, 2018 - frontiersin.org
Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …
Basal cell carcinoma: from pathophysiology to novel therapeutic approaches
Basal cell carcinoma (BCC) is the most common human cancer worldwide, and is a subtype
of nonmelanoma skin cancer, characterized by a constantly increasing incidence due to an …
of nonmelanoma skin cancer, characterized by a constantly increasing incidence due to an …
Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies
S Tanabe, S Quader, H Cabral, R Ono - Frontiers in pharmacology, 2020 - frontiersin.org
The mechanism of epithelial-mesenchymal transition (EMT) consists of the cellular
phenotypic transition from epithelial to mesenchymal status. The cells exhibiting EMT exist in …
phenotypic transition from epithelial to mesenchymal status. The cells exhibiting EMT exist in …
The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy
MicroRNAs (miRNAs) are a large family of small non-coding RNAs that negatively regulate
protein-coding gene expression post-transcriptionally via base pairing between the 5 …
protein-coding gene expression post-transcriptionally via base pairing between the 5 …
LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 …
SP Li, HX Xu, Y Yu, JD He, Z Wang, YJ Xu… - …, 2016 - pmc.ncbi.nlm.nih.gov
Highly upregulated in liver cancer (HULC), a lncRNA that is considered a key molecule in
human liver cancer, has recently been revealed to be involved in hepatocellular carcinoma …
human liver cancer, has recently been revealed to be involved in hepatocellular carcinoma …
H19 activates Wnt signaling and promotes osteoblast differentiation by functioning as a competing endogenous RNA
Bone homeostasis is tightly orchestrated and maintained by the balance between
osteoblasts and osteoclasts. Recent studies have greatly expanded our understanding of …
osteoblasts and osteoclasts. Recent studies have greatly expanded our understanding of …
[HTML][HTML] Interplay between microRNAs and WNT/β-catenin signalling pathway regulates epithelial–mesenchymal transition in cancer
The WNT/β-catenin signalling implies its significance in maintaining an epithelial cell
phenotype, proper cell–cell junctions, and tissue homeostasis. Dysregulation of the …
phenotype, proper cell–cell junctions, and tissue homeostasis. Dysregulation of the …