Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Association between vancomycin minimum inhibitory concentration and mortality among patients with Staphylococcus aureus bloodstream infections: a systematic …

AC Kalil, TC Van Schooneveld, PD Fey, ME Rupp - Jama, 2014 - jamanetwork.com
Importance Staphylococcus aureusbacteremia (SAB) is a worldwide problem. It is unclear
whether higher-vancomycin minimum inhibitory concentration (MIC) is associated with …

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America …

AC Kalil, ML Metersky, M Klompas… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

[HTML][HTML] Evaluation of vancomycin MIC creep in methicillin-resistant Staphylococcus aureus infections—a systematic review and meta-analysis

R Diaz, V Afreixo, E Ramalheira, C Rodrigues… - Clinical Microbiology …, 2018 - Elsevier
Objectives Vancomycin is currently the primary option treatment for methicillin-resistant
Staphylococcus aureus (MRSA). However, an increasing number of MRSA isolates with …

Area under the concentration–time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant …

Y Jung, KH Song, J eun Cho, H Kim, NH Kim… - International journal of …, 2014 - Elsevier
There have been few clinical studies on the association between the 24-h area under the
concentration–time curve (AUC 24) to minimum inhibitory concentration (MIC) ratio and …

Daptomycin improves outcomes regardless of vancomycin MIC in a propensity-matched analysis of methicillin-resistant Staphylococcus aureus bloodstream infections

KC Claeys, EJ Zasowski, AM Casapao… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Vancomycin remains the mainstay treatment for methicillin-resistant Staphylococcus aureus
(MRSA) bloodstream infections (BSIs) despite increased treatment failures. Daptomycin has …

The safety and efficacy of high versus low vancomycin trough levels in the treatment of patients with infections caused by methicillin-resistant Staphylococcus aureus …

S Tongsai, P Koomanachai - BMC research notes, 2016 - Springer
Background Recent guidelines have recommended vancomycin trough levels of 15–20
mg/L for treatment of serious infections caused by methicillin-resistant Staphylococcus …

Bacteremia, Sepsis, and Infective Endocarditis Associated with Staphylococcus aureus

SP Bergin, TL Holland, VG Fowler… - … , Immunology, Therapy and …, 2017 - Springer
Bacteremia and infective endocarditis (IE) are important causes of morbidity and mortality
associated with Staphylococcus aureus infections. Increasing exposure to healthcare …

Predictive factors for early mortality among patients with methicillin-resistant Staphylococcus aureus bacteraemia

O Gasch, M Camoez, MA Dominguez… - Journal of …, 2013 - academic.oup.com
Objectives A high proportion of patients with methicillin-resistant Staphylococcus aureus
(MRSA) bacteraemia die within a few days of the onset of infection. However, predictive …

Titania nanotube architectures synthesized on 3d-printed ti-6al-4v implant and assessing vancomycin release protocols

H Chunate, J Khamwannah, AAA Aliyu, S Tantavisut… - Materials, 2021 - mdpi.com
The aim of this study is to synthesize Titania nanotubes (TNTs) on the 3D-printed Ti-6Al-4V
surface and investigate the loading of antibacterial vancomycin drug dose of 200 ppm for …