Inflammatory microenvironment remodelling by tumour cells after radiotherapy
M McLaughlin, EC Patin, M Pedersen, A Wilkins… - Nature Reviews …, 2020 - nature.com
The development of immune checkpoint inhibitors (ICIs) is revolutionizing the way we think
about cancer treatment. Even so, for most types of cancer, only a minority of patients …
about cancer treatment. Even so, for most types of cancer, only a minority of patients …
Hypoxia: a key player in antitumor immune response. A review in the theme: cellular responses to hypoxia
MZ Noman, M Hasmim, Y Messai… - … of Physiology-Cell …, 2015 - journals.physiology.org
The tumor microenvironment is a complex system, playing an important role in tumor
development and progression. Besides cellular stromal components, extracellular matrix …
development and progression. Besides cellular stromal components, extracellular matrix …
Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer
Photothermal therapy (PTT) is a promising cancer treatment modality, but PTT generally
requires direct access to the source of light irradiation, thus precluding its utility against …
requires direct access to the source of light irradiation, thus precluding its utility against …
Radiation effects on antitumor immune responses: current perspectives and challenges
T Walle, R Martinez Monge… - … in medical oncology, 2018 - journals.sagepub.com
Radiotherapy (RT) is currently used in more than 50% of cancer patients during the course
of their disease in the curative, adjuvant or palliative setting. RT achieves good local control …
of their disease in the curative, adjuvant or palliative setting. RT achieves good local control …
Radiotherapy–immunotherapy combinations–perspectives and challenges
Ionizing radiation has historically been used to treat cancer by killing tumour cells, in
particular by inducing DNA damage. This view of radiotherapy (RT) as a simple cytotoxic …
particular by inducing DNA damage. This view of radiotherapy (RT) as a simple cytotoxic …
Peptide-based vaccine for cancer therapies
Different strategies based on peptides are available for cancer treatment, in particular to
counter-act the progression of tumor growth and disease relapse. In the last decade, in the …
counter-act the progression of tumor growth and disease relapse. In the last decade, in the …
Cancer vaccines: Adjuvant potency, importance of age, lifestyle, and treatments
S Cuzzubbo, S Mangsbo, D Nagarajan… - Frontiers in …, 2021 - frontiersin.org
Although the discovery and characterization of multiple tumor antigens have sparked the
development of many antigen/derived cancer vaccines, many are poorly immunogenic and …
development of many antigen/derived cancer vaccines, many are poorly immunogenic and …
Immunomodulation by ionizing radiation—impact for design of radio‐immunotherapies and for treatment of inflammatory diseases
Ionizing radiation is often regarded as an element of danger. But, danger responses on the
cellular and molecular level are often beneficial with regard to the induction of anti‐tumor …
cellular and molecular level are often beneficial with regard to the induction of anti‐tumor …
Immune modulation of head and neck squamous cell carcinoma and the tumor microenvironment by conventional therapeutics
Head and neck squamous cell carcinoma (HNSCC) accounts for more than 600,000 cases
and 380,000 deaths annually worldwide. Although human papillomavirus (HPV)–associated …
and 380,000 deaths annually worldwide. Although human papillomavirus (HPV)–associated …
Potential role of CXCR4 targeting in the context of radiotherapy and immunotherapy of cancer
F Eckert, K Schilbach, L Klumpp, L Bardoscia… - Frontiers in …, 2018 - frontiersin.org
Cancer immunotherapy has been established as standard of care in different tumor entities.
After the first reports on synergistic effects with radiotherapy and the induction of abscopal …
After the first reports on synergistic effects with radiotherapy and the induction of abscopal …