The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory
hypokinetic and hyperkinetic movement disorders, and it is being explored for a variety of …

The roles of the basal ganglia (BG) in motor control are much debated. Many influential
hypotheses have grown from studies in which output signals of the BG were not blocked, but …

Deep brain stimulation (DBS) is an established medical therapy for the treatment of
movement disorders and shows great promise for several other neurological disorders …

Motor thalamus (Mthal) is implicated in the control of movement because it is strategically
located between motor areas of the cerebral cortex and motor-related subcortical structures …

The initiation and propagation of action potentials (APs) places high demands on the
energetic resources of neural tissue. Each AP forces ATP-driven ion pumps to work harder …

Deep brain stimulation in the subthalamic nucleus is an effective and safe surgical
procedure that has been shown to reduce the motor dysfunction of patients with advanced …

The investigation of the human intelligence, cognitive systems and functional complexity of
human brain is significantly facilitated by high-performance computational platforms. In this …

Brain stimulation is a promising therapy for several neurological disorders, including
Parkinson's disease. Stimulation parameters are selected empirically and are limited to the …

Deep brain stimulation (DBS) has been successfully applied in various neurodegenerative
diseases as an effective symptomatic treatment. However, its mechanisms of action within …