Recent advances in small-angle scattering techniques for MOF colloidal materials

X **ng, W Cheng, S Zhou, H Liu, Z Wu - Advances in Colloid and Interface …, 2024 - Elsevier
This paper reviews the recent progress of small angle scattering (SAS) techniques, mainly
including X-ray small angle scattering technique (SAXS) and neutron small angle scattering …

Peptide bundlemer networks or lattices: controlling cross-linking and self-assembly using protein-like display of chemistry

AL McCahill, T Zhang, JG Saven, CJ Kloxin… - ACS …, 2024 - ACS Publications
Coiled-coil 'bundlemer'peptides were selectively modified with allyloxycarbonyl (alloc)-
protected lysine, a non-natural amino acid containing an alkene on its side chain. The …

Computational design of homotetrameric peptide bundle variants spanning a wide range of charge states

R Guo, NJ Sinha, R Misra, Y Tang… - …, 2022 - ACS Publications
With the ability to design their sequences and structures, peptides can be engineered to
realize a wide variety of functionalities and structures. Herein, computational design was …

[HTML][HTML] Competition between cross-linking and force-induced local conformational changes determines the structure and mechanics of labile protein networks

MDG Hughes, D West, R Wurr, S Cussons… - Journal of Colloid and …, 2025 - Elsevier
Folded protein hydrogels are emerging as promising new materials for medicine and
healthcare applications. Folded proteins can be modelled as colloids which exhibit site …

Coarse-Grain Model of Ultrarigid Polymer Rods Comprising Bifunctionally Linked Peptide Bundlemers

T Zhang, DB Yang, CJ Kloxin, DJ Pochan… - …, 2024 - ACS Publications
Computationally designed homotetrameric helical peptide bundles have been
functionalized at their N-termini to achieve supramolecular polymers, wherein individual …

Complementary Peptide Interactions Support the Ultra-Rigidity of Polymers of De Novo Designed Click-Functionalized Bundlemers

DB Yang, T Zhang, JE Blum, CJ Kloxin… - The Journal of …, 2025 - ACS Publications
Computationally designed 29-residue peptides yield tetra-α-helical bundles with D 2
symmetry. The “bundlemers” can be bifunctionally linked via thiol-maleimide cross-links at …

Liquid Crystal Behavior of Uniform Short Rods Made from Computationally Designed Parallel Coiled Coil Building Blocks

Z Zhang, JE Blum, R Guo, CJ Kloxin, JG Saven… - ACS Macro …, 2024 - ACS Publications
Parallel, homotetrameric coiled coils were computationally designed using 29 amino acid
peptides. These parallel coiled coils, called “bundlemers”, have C 2 symmetry, with all N …

Computational design of single-peptide nanocages with nanoparticle templating

JA Villegas, NJ Sinha, N Teramoto, CD Von Bargen… - Molecules, 2022 - mdpi.com
Protein complexes perform a diversity of functions in natural biological systems. While
computational protein design has enabled the development of symmetric protein complexes …

Identification of Surfactant Impact on a Monoclonal Antibody Characterization via HPLC-Separation Based and Biophysical Methods

K Guo, J Song, P Bennington, AJ Pavon… - Pharmaceutical …, 2024 - Springer
Abstract Purpose or Objective Surfactants, including polysorbates and poloxamers, play a
crucial role in the formulation of therapeutic proteins by acting as solubilizing and stabilizing …

Aqueous self-assembly of cylindrical and tapered bottlebrush block copolymers

C Vu, NA Amara, M Alaboalirat, E Nativ-Roth, R Zalk… - 2024 - chemrxiv.org
Self-assembly of amphiphilic bottlebrush block copolymers (BCPs), which have backbones
with two types of densely grafted side chains, is less well understood compared to their …