Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

Sex characteristics exhibit significant disparities in various human diseases, including
prevalent cardiovascular diseases, cancers, metabolic disorders, autoimmune diseases …

The study of reproductive isolation and species barriers frequently focuses on mitochondrial
genomes and has produced two alternative and almost diametrically opposed narratives. On …

Mitochondria are key to energy conversion in virtually all eukaryotes. Intriguingly, despite
billions of years of evolution inside the eukaryote, mitochondria have retained their own …

Metazoans exist only with a continuous and rich supply of chemical energy from oxidative
phosphorylation in mitochondria. The oxidative phosphorylation machinery that mediates …

Genetic, developmental, biochemical, and environmental variables interact intricately to
produce sex differences. The significance of sex differences in cancer susceptibility is being …

Diversifying selection on metabolic pathways can reduce intraspecific gene flow and
promote population divergence. An opportunity to explore this arises from mitonuclear …

Cellular metabolism is regulated by enzyme complexes within the mitochondrion, the
function of which are sensitive to the prevailing temperature. Such thermal sensitivity …

Metabolic processes in eukaryotic cells depend on interactions between mitochondrial and
nuclear gene products (mitonuclear interactions). These interactions could have a direct role …

Recent data from mitochondrial genomics and proteomics research demonstrate the
existence of several atypical mitochondrial protein-coding genes (other than the standard …