Applications of palladium-catalyzed C–N cross-coupling reactions

P Ruiz-Castillo, SL Buchwald - Chemical reviews, 2016‏ - ACS Publications
Pd-catalyzed cross-coupling reactions that form C–N bonds have become useful methods to
synthesize anilines and aniline derivatives, an important class of compounds throughout …

Guanidines: from classical approaches to efficient catalytic syntheses

C Alonso-Moreno, A Antinolo… - Chemical Society …, 2014‏ - pubs.rsc.org
From organosuperbases capable of base-catalyzing organic reactions, through versatile
'ligand-sets' for use in coordination chemistry, to fundamental entities in medicinal chemistry …

Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters, aryl isothiocyanates, amines and cyclic ethers

Y Lv, H Ding, J You, W Wei, D Yi - Chinese Chemical Letters, 2024‏ - Elsevier
An additive-free and environmentally friendly strategy has been realized for the construction
of S-substituted isothioureas through visible-light-induced multicomponent reaction starting …

Catalytic methods for aromatic C–H amination: an ideal strategy for nitrogen-based functional molecules

J Jiao, K Murakami, K Itami - ACS Catalysis, 2016‏ - ACS Publications
Transformations of aromatic compounds into the corresponding amines, amides, and imides
through carbon–hydrogen (C–H) bond functionalization represent one of the most step-and …

Enantioselective Synthesis of Atropisomeric Biaryls by Pd‐Catalyzed Asymmetric Buchwald–Hartwig Amination

P Zhang, XM Wang, Q Xu, CQ Guo, P Wang… - Angewandte …, 2021‏ - Wiley Online Library
N− C Biaryl atropisomers are prevalent in natural products and bioactive drug molecules.
However, the enantioselective synthesis of such molecules has not developed significantly …

7-Azaindole N-Oxide (7-AINO) Mediated Cu-Catalyzed N-Arylation: Mechanistic Investigation into the Role of Fluoride Ions

K Mondal, N Mukhopadhyay, S Patra, T Roy… - ACS Catalysis, 2023‏ - ACS Publications
A Cu (II) fluoride-catalyzed N-arylation of 7-azaindole N-oxides (7-AINO) has been
developed using boronic acid under base-free conditions. During the process, a …

[PDF][PDF] Sustainable synthesis of diverse privileged heterocycles by palladium‐catalyzed aerobic oxidative isocyanide insertion

T Vlaar, RC Cioc, P Mampuys, BUW Maes… - Angewandte Chemie …, 2012‏ - academia.edu
Heterocycles containing a guanidine moiety are of great importance in medicinal chemistry
(Scheme 1).[1] As a result, several methods for the synthesis of these “privileged scaffolds” …

Metal-catalyzed reactions of organic nitriles and boronic acids to access diverse functionality

HN Dhara, A Rakshit, T Alam, BK Patel - Organic & Biomolecular …, 2022‏ - pubs.rsc.org
The nitrile or cyano (–CN) group is one of the most appreciated and effective functional
groups in organic synthesis, having a polar unsaturated C–N triple bond. Despite sufficient …

[PDF][PDF] Copper-mediated synthesis of 1, 2, 3-triazoles from N-tosylhydrazones and anilines

Z Chen, Q Yan, Z Liu, Y Xu, Y Zhang - Angew. Chem., Int. Ed, 2013‏ - researchgate.net
1, 2, 3-Triazoles have found wide application in chemistry, biology, and materials science.[1]
Therefore, general methods for their synthesis are of considerable importance.[2] …

Copper-catalyzed oxidative diamination of terminal alkynes by amidines: synthesis of 1, 2, 4-trisubstituted imidazoles

J Li, L Neuville - Organic Letters, 2013‏ - ACS Publications
An efficient copper-catalyzed synthesis of 1, 2, 4-trisubstituted imidazoles using amidines
and terminal alkynes has been developed. Overall, the oxidative process, which involves …