Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

Metabolic syndrome is a growing cause of morbidity and mortality worldwide. Metabolic
syndrome is characterized by the presence of a variety of metabolic disturbances including …

The increased prevalence of obesity and related comorbidities is a major public health
problem. While genetic factors undoubtedly play a role in determining individual …

Early pregnancy in mammals requires complex and highly orchestrated cellular and
molecular interactions between specialized cells within the endometrium and the conceptus …

The risk of obesity (OB) in adulthood is strongly influenced by maternal body composition.
Here we examined the hypothesis that maternal OB influences white adipose tissue (WAT) …

Rapidly growing evidences link maternal lifestyle and prenatal factors with serious health
consequences and diseases later in life. Extensive epidemiological studies have identified a …

Objective Epigenetic modifications contribute to the etiology of type 2 diabetes. Method We
performed genome-wide methylome and transcriptome analysis in liver from severely obese …

Obesity is becoming an epidemic health problem. During the last years not only genetic but
also, and primarily, environmental factors have been supposed to contribute to the …

The Developmental Origins of Health and Disease hypothesis holds that alterations to
homeostasis during critical periods of development can predispose individuals to adult …

Evidence from both human and animal studies has shown that the prenatal and early
postnatal environments influence susceptibility to chronic disease in later life and suggests …