Introduction: Allostatic load refers to the cumulative burden of chronic stress and life events.
It involves the interaction of different physiological systems at varying degrees of activity …

Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Recent allostatic–interoceptive explanations using predictive coding models propose that
efficient regulation of the body's internal milieu is necessary to correctly anticipate …

Background: Neighborhoods are critical to understanding how environments influence
health outcomes. Prolonged environmental stressors, such as a lack of green spaces and …

Allostatic load (AL) refers to prolonged dysregulation related to chronic stress that affects
brain regions such as the hippocampus, amygdala, and prefrontal cortex (PFC). Higher …

Allostatic load represents the 'wear and tear'of chronic stress on the brain and body that may
differ between men and women. A small but growing number of studies are assessing …

Although schizophrenia is a brain disorder, increasing evidence suggests that there may be
body-wide involvement in this illness. However, direct evidence of brain structures involved …

This study explored the associations between specific profiles of biological dysregulation
and mental health outcomes in a national, community sample of healthy adults in the United …

Psychiatric disorders are complex, disabling, and chronic conditions that are often
accompanied by one or more systemic medical comorbidities. In this narrative review, we …

We examined the empirical validity of a staging model of psychotic disorders primarily based
on their long-term course. The model distinguished 6 consecutive stages (2A, 2B, 3A, 3B …