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Small molecules regulating reactive oxygen species homeostasis for cancer therapy
J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …
The mechanism (s) of action of antioxidants: From scavenging reactive oxygen/nitrogen species to redox signaling and the generation of bioactive secondary …
A Hunyadi - Medicinal research reviews, 2019 - Wiley Online Library
Small molecule, dietary antioxidants exert a remarkably broad range of bioactivities, and
many of these can be explained by the influence of antioxidants on the redox homeostasis …
many of these can be explained by the influence of antioxidants on the redox homeostasis …
[PDF][PDF] Synthesis and biological activities of 3, 5-disubstituted-4-hydroxycinnamic acids linked to a functionalized coumarin
As part of our interest in the coumarin chemical nucleus, a series of 3, 5-disubstituted-4-
hydroxycinnamic acids to which 6-hydroxy-7-methoxy-4-methyl-3-isopropylcoumarin is …
hydroxycinnamic acids to which 6-hydroxy-7-methoxy-4-methyl-3-isopropylcoumarin is …
Bridging free radical chemistry with drug discovery: A promising way for finding novel drugs efficiently
ZQ Liu - European Journal of Medicinal Chemistry, 2020 - Elsevier
Many diseases have been regarded to correlate with the in vivo oxidative damages, which
are caused by overproduced free radicals from metabolic process or reactive oxygen …
are caused by overproduced free radicals from metabolic process or reactive oxygen …
[HTML][HTML] Oxidized resveratrol metabolites as potent antioxidants and xanthine oxidase inhibitors
OG Agbadua, N Kúsz, R Berkecz, T Gáti, G Tóth… - Antioxidants, 2022 - mdpi.com
Resveratrol is a well-known natural polyphenol with a plethora of pharmacological activities.
As a potent antioxidant, resveratrol is highly oxidizable and readily reacts with reactive …
As a potent antioxidant, resveratrol is highly oxidizable and readily reacts with reactive …
A mini-review: Exploring the application prospects of the three major rules in the field of antioxidants
Y Hu, Z Zheng, D Zhai, P Liang, Z Wang… - Journal of Molecular …, 2024 - Elsevier
Antioxidants are substances that can delay or inhibit oxidation reactions and are widely
used in various fields such as medicine, cosmetics, and food industries. Although the three …
used in various fields such as medicine, cosmetics, and food industries. Although the three …
[HTML][HTML] Antioxidant and Cytoprotective Effects of (−)-Epigallocatechin-3-(3″-O-methyl) Gallate
Reactive oxygen species (ROS) are generated from diverse cellular processes or external
sources such as chemicals, pollutants, or ultraviolet (UV) irradiation. Accumulation of …
sources such as chemicals, pollutants, or ultraviolet (UV) irradiation. Accumulation of …
[HTML][HTML] A review of phytochemicals and bioactive properties in the Proteaceae family: A promising source of functional food
In recent decades, natural plant-based foods have been increasingly used to improve
human health due to unhealthy modern dietary patterns, such as the consumption of foods …
human health due to unhealthy modern dietary patterns, such as the consumption of foods …
Bioactive components and anticancer activities of spray-dried New Zealand tamarillo powder
Tamarillo fruit contains many phytochemicals that have beneficial therapeutic and nutritional
properties. Spray-drying is widely used to preserve fruit puree in powder form. However, to …
properties. Spray-drying is widely used to preserve fruit puree in powder form. However, to …
Novel acrylonitrile derived imidazo [4, 5-b] pyridines as antioxidants and potent antiproliferative agents for pancreatic adenocarcinoma
IB Pavlinac, L Persoons, D Daelemans… - International journal of …, 2024 - Elsevier
We present the design, synthesis, computational analysis, and biological assessment of
several acrylonitrile derived imidazo [4, 5-b] pyridines, which were evaluated for their …
several acrylonitrile derived imidazo [4, 5-b] pyridines, which were evaluated for their …