Astrocytes as guardians of neuronal excitability: mechanisms underlying epileptogenesis
QP Verhoog, L Holtman, E Aronica… - Frontiers in …, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …
The role of glial-specific Kir4. 1 in normal and pathological states of the CNS
SE Nwaobi, VA Cuddapah, KC Patterson… - Acta …, 2016 - Springer
Kir4. 1 is an inwardly rectifying K+ channel expressed exclusively in glial cells in the central
nervous system. In glia, Kir4. 1 is implicated in several functions including extracellular K+ …
nervous system. In glia, Kir4. 1 is implicated in several functions including extracellular K+ …
Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats
In the spinal cord, neuron and glial cells actively interact and contribute to neurofunction.
Surprisingly, both cell types have similar receptors, transporters and ion channels and also …
Surprisingly, both cell types have similar receptors, transporters and ion channels and also …
Kir4. 1-dependent astrocyte-fast motor neuron interactions are required for peak strength
Diversified neurons are essential for sensorimotor function, but whether astrocytes become
specialized to optimize circuit performance remains unclear. Large fast α-motor neurons …
specialized to optimize circuit performance remains unclear. Large fast α-motor neurons …
Identification of a circRNA-miRNA-mRNA network to explore the effects of circRNAs on pathogenesis and treatment of spinal cord injury
P Peng, B Zhang, J Huang, C **ng, W Liu, C Sun… - Life sciences, 2020 - Elsevier
Aims Many studies have demonstrated that circRNAs are closely associated with human
diseases. Nonetheless, the potential mechanism by which circRNAs impacts spinal cord …
diseases. Nonetheless, the potential mechanism by which circRNAs impacts spinal cord …
Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling
Astrocytes are endowed with the machinery to sense and respond to neuronal activity.
Recent work has demonstrated that astrocytes play important physiological roles in the CNS …
Recent work has demonstrated that astrocytes play important physiological roles in the CNS …
GABA and central neuropathic pain following spinal cord injury
YS Gwak, CE Hulsebosch - Neuropharmacology, 2011 - Elsevier
Spinal cord injury induces maladaptive synaptic transmission in the somatosensory system
that results in chronic central neuropathic pain. Recent literature suggests that glial-neuronal …
that results in chronic central neuropathic pain. Recent literature suggests that glial-neuronal …
Estrogen attenuates local inflammasome expression and activation after spinal cord injury
estradiol (E2) is a neuroprotective hormone with a high anti-inflammatory potential in
different neurological disorders. The inflammatory response initiated by spinal cord injury …
different neurological disorders. The inflammatory response initiated by spinal cord injury …
Main cations and cellular biology of traumatic spinal cord injury
Traumatic spinal cord injury is a life-changing condition with a significant socio-economic
impact on patients, their relatives, their caregivers, and even the community. Despite …
impact on patients, their relatives, their caregivers, and even the community. Despite …
Toll-like receptors in central nervous system injury and disease: a focus on the spinal cord
Toll-like receptors (TLRs) are best known for recognizing pathogens and initiating an innate
immune response to protect the host. However, they also detect tissue damage and induce …
immune response to protect the host. However, they also detect tissue damage and induce …