Chordoma is a rare bone cancer that is aggressive, locally invasive, and has a poor
prognosis. Chordomas are thought to arise from transformed remnants of notochord and …

Chordoma is a low-grade notochordal tumor of the skull base, mobile spine and sacrum
which behaves malignantly and confers a poor prognosis despite indolent growth patterns …

We hypothesised that the use of computer navigation-assisted surgery for pelvic and sacral
tumours would reduce the risk of an intralesional margin. We reviewed 31 patients (18 men …

Aberrantly expressed miRNAs play a crucial role in the development of multiple cancer
types, including chordoma. However, the detailed molecular mechanisms are unclear and …

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Background Spinal chordomas are rare primary osseous tumors that arise from the
remnants of the notochord. They are commonly considered slow-growing, locally invasive …

Chordoma is a rare tumor that occurs along the axial spine in pediatrics and adults, with an
incidence of approximately 350 cases per year in the United States. While typically …

Object Chordoma is a malignant bone neoplasm hypothesized to arise from notochordal
remnants along the length of the neuraxis. Recent genomic investigation of chordomas has …

Background Sacral chordomas are rare low-to-intermediate grade malignant tumours, which
arise from remnants of the embryonic notochord. This review explores prognostic factors in …

En bloc spinal tumor resections are technically demanding procedures with high morbidity
because of the conventionally large exposure area and aggressive resection goals …