The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

Brain edema is a severe stroke complication that is associated with prolonged
hospitalization and poor outcomes. Swollen tissues in the brain compromise cerebral …

Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All
potential pharmacological interventions have failed in clinical trials, meaning that symptom …

The belief that the vertebrate brain functions normally without classical lymphatic drainage
vessels has been held for many decades. On the contrary, new findings show that functional …

Brain swelling causes morbidity and mortality in various brain injuries and diseases but
lacks effective treatments. Brain swelling is linked to the influx of water into perivascular …

Multiple randomized clinical trials have supported the use of mechanical thrombectomy (MT)
as standard of care in the treatment of large vessel occlusion acute ischemic stroke. Optimal …

Ischemic stroke is associated with increasing morbidity and has become the main cause of
death and disability worldwide. Cerebral edema is a serious complication arising from …

Cerebral edema following ischemic stroke is predictive of the severity of the eventual stroke
related damage, however the effective treatment is limited. The glymphatic system is a …

MicroRNA-29b (miR-29b) is involved in regulating ischemia process, but the molecular
mechanism is unclear. In this work, we explored the function of miR-29b in cerebral …

Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …