The role and regulation of integrins in cell migration and invasion

MR Chastney, J Kaivola, VM Leppänen… - … Reviews Molecular Cell …, 2025 - nature.com
Integrin receptors are the main molecular link between cells and the extracellular matrix
(ECM) as well as mediating cell–cell interactions. Integrin–ECM binding triggers the …

[HTML][HTML] Novel tools to study cell-ECM interactions, cell adhesion dynamics and migration

M Dibus, O Joshi, J Ivaska - Current Opinion in Cell Biology, 2024 - Elsevier
Integrin-mediated cell adhesion is essential for cell migration, mechanotransduction and
tissue integrity. In vivo, these processes are regulated by complex physicochemical signals …

Bioprinted biomimetic hydrogel matrices guiding stem cell aggregates for enhanced chondrogenesis and cartilage regeneration

Y Liu, L Du, H Zhang, G Li, Y Luo, Z Hu, R Xu… - Journal of Materials …, 2024 - pubs.rsc.org
Articular cartilage tissue has limited self-repair capabilities, with damage frequently
progressing to irreversible degeneration. Engineered tissues constructed through …

[HTML][HTML] Cell cycle control by cell-matrix interactions

MJ Jones, MC Jones - Current Opinion in Cell Biology, 2024 - Elsevier
Cell adhesion to the extracellular matrix (ECM) is required for normal cell cycle progression
and accurate cell division. However, how cell adhesion to the wide range of ECM proteins …

Monitoring the mass, eigenfrequency, and quality factor of mammalian cells

S Herzog, G Fläschner, I Incaviglia, JC Arias… - Nature …, 2024 - nature.com
The regulation of mass is essential for the development and homeostasis of cells and
multicellular organisms. However, cell mass is also tightly linked to cell mechanical …

Deep learning image recognition-assisted atomic force microscopy for single-cell efficient mechanics in co-culture environments

X Yang, Y Yang, Z Zhang, M Li - Langmuir, 2023 - ACS Publications
Atomic force microscopy (AFM)-based force spectroscopy assay has become an important
method for characterizing the mechanical properties of single living cells under aqueous …

Automated high-throughput atomic force microscopy single-cell nanomechanical assay enabled by deep learning-based optical image recognition

R **ao, Y Zhang, M Li - Nano Letters, 2024 - ACS Publications
Mechanical forces are essential for life activities, and the mechanical phenotypes of single
cells are increasingly gaining attention. Atomic force microscopy (AFM) has been a standard …

Infrared nanosensors of pico-to micro-newton forces

N Fardian-Melamed, A Skripka, C Lee… - arxiv preprint arxiv …, 2024 - arxiv.org
Mechanical force is an essential feature for many physical and biological processes. 1-12
Remote measurement of mechanical signals with high sensitivity and spatial resolution is …

Non-IgE-reactive allergen peptides deteriorate the skin barrier in house dust mite-sensitized atopic dermatitis patients

K Pfisterer, M Wielscher, D Samardzic… - Frontiers in Cell and …, 2023 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by type 2
cytokine-driven skin inflammation and epithelial barrier dysfunction. The latter is believed to …

Finite Element Modeling of Cells Adhering to a Substrate: An Overview

L Santoro, L Vaiani, A Boccaccio, L Lamberti… - Applied Sciences, 2024 - mdpi.com
In tissue formation and regeneration processes, cells often move collectively, maintaining
connections through intercellular adhesions. However, the specific roles of cell–substrate …