Genomic, epigenomic and transcriptomic landscape of glioblastoma
The mostly aggressive and extremely malignant type of central nervous system is
Glioblastoma (GBM), which is characterized by an extremely short average survival time of …
Glioblastoma (GBM), which is characterized by an extremely short average survival time of …
Epigenetic Biomarkers in Alzheimer's Disease: Diagnostic and Prognostic Relevance
Alzheimer's disease (AD) is a leading cause of cognitive decline in the aging population,
presenting a critical need for early diagnosis and effective prognostic tools. Epigenetic …
presenting a critical need for early diagnosis and effective prognostic tools. Epigenetic …
EPIC-0628 abrogates HOTAIR/EZH2 interaction and enhances the temozolomide efficacy via promoting ATF3 expression and inhibiting DNA damage repair in …
E Yang, B Hong, Y Wang, Q Wang, J Zhao, X Cui, Y Wu… - Cancer Letters, 2024 - Elsevier
The efficacy of temozolomide (TMZ) treatment in glioblastoma (GBM) is influenced by
various mechanisms, mainly including the level of O 6-methylguanine-DNA …
various mechanisms, mainly including the level of O 6-methylguanine-DNA …
Role of long noncoding RNAs in the regulation of alternative splicing in glioblastoma
B Yadav, P Yadav, S Yadav, AK Pandey - Drug Discovery Today, 2024 - Elsevier
Glioblastoma multiforme (GBM) is a highly severe primary brain tumor. Despite extensive
research, effective treatments remain elusive. Long noncoding RNAs (lncRNAs) play a …
research, effective treatments remain elusive. Long noncoding RNAs (lncRNAs) play a …
Unraveling the noncoding RNA landscape in glioblastoma: from pathogenesis to precision therapeutics
Glioblastoma (GBM) is an aggressive type IV brain tumor that originates from astrocytes and
has a poor prognosis. Despite intensive research, survival rates have not significantly …
has a poor prognosis. Despite intensive research, survival rates have not significantly …
Unraveling the role of LncRNAs in glioblastoma progression: insights into signaling pathways and therapeutic potential
Glioblastoma (GBM) is one of the most aggressive types of brain cancer, characterized by its
poor prognosis and low survival rate despite current treatment modalities. Because GBM is …
poor prognosis and low survival rate despite current treatment modalities. Because GBM is …
[HTML][HTML] Epigenetic Biomarkers in Thrombophilia-Related Pregnancy Complications: Mechanisms, Diagnostic Potential, and Therapeutic Implications: A Narrative …
CR Bardan, I Ioniță, M Iordache… - International Journal of …, 2024 - mdpi.com
Pregnancy complications associated with thrombophilia represent significant risks for
maternal and fetal health, leading to adverse outcomes such as pre-eclampsia, recurrent …
maternal and fetal health, leading to adverse outcomes such as pre-eclampsia, recurrent …
Hidden regulators: the emerging roles of lncRNAs in brain development and disease
F Alammari, EM Al-Hujaily, A Alshareeda… - Frontiers in …, 2024 - frontiersin.org
Long non-coding RNAs (lncRNAs) have emerged as critical players in brain development
and disease. These non-coding transcripts, which once considered as “transcriptional junk,” …
and disease. These non-coding transcripts, which once considered as “transcriptional junk,” …
Long non-coding RNAs; potential contributors in cancer chemoresistance through modulating diverse molecular mechanisms and signaling pathways
One of the mainstays of cancer treatment is chemotherapy. Drug resistance, however,
continues to be the primary factor behind clinical treatment failure. Gene expression is …
continues to be the primary factor behind clinical treatment failure. Gene expression is …
The role of lncRNAs in the interplay of signaling pathways and epigenetic mechanisms in glioma
Gliomas, highly aggressive tumors of the central nervous system, present overwhelming
challenges due to their heterogeneity and therapeutic resistance. Glioblastoma multiforme …
challenges due to their heterogeneity and therapeutic resistance. Glioblastoma multiforme …