Potentiality and Synthesis of O‐and N‐Heterocycles: Pd‐Catalyzed Cyclocarbonylative Sonogashira Coupling as a Valuable Route to Phthalans, Isochromans, and …

G Albano, LA Aronica - European Journal of Organic Chemistry, 2017 - Wiley Online Library
Oxygen and nitrogen heterocycle systems are found in a vast number of natural substrates
and biologically active molecules. In particular, phthalan, isochroman, and isoindoline …

ortho-Halobenzyl Halides as Precursors for the Synthesis of Five-to Nine-Membered Ring Structures Employing Transition Metals as Catalysts

N Aljaar, M Shtaiwi, BF Ali, M Al-Refai, K Kant… - …, 2024 - thieme-connect.com
This review highlights the multifaceted usefulness of o-halobenzyl halides as pivotal
substrates for the construction of five-to nine-membered cyclic structures with the aid of …

The study of metal-free and palladium-catalysed synthesis of benzochromenes via direct C–H arylation using unactivated aryl benzyl ethers derived from essential oils …

MCO Villamizar, FI Zubkov, CEP Galvis… - Organic Chemistry …, 2017 - pubs.rsc.org
The synthesis of 6H-benzo [c] chromenes from unactivated 2-bromo aryl benzyl ethers was
studied through two approaches:(i) the transition-metal-free intramolecular dehydrohalide …

Recent advances in phthalan and coumaran chemistry

E Ilya, L Kulikova, EV Van der Eycken… - …, 2018 - Wiley Online Library
Oxygen‐containing heterocycles are common in biologically active compounds. In
particular, phthalan and coumaran cores are found in pharmaceuticals, organic electronics …

Palladium‐Catalyzed Synthesis of 6H‐Dibenzo [c, h] chromenes and 5, 6‐Dihydrobenzo [c] phenanthridines: Application to the Synthesis of Dibenzo [c, h] chromene …

S Pramanik, M Jash, D Mondal… - Advanced Synthesis & …, 2019 - Wiley Online Library
Abstract 6H‐Dibenzo [c, h] chromenes and 5, 6‐dihydrobenzo [c] phenanthridines have
been synthesized via Palladium (II)‐catalyzed domino reactions of acetylenic substrates …

Zinc-mediated allylation and benzylation of phenylazocarboxylic esters

R Lasch, MR Heinrich - The Journal of organic chemistry, 2015 - ACS Publications
Allylation and benzylation of phenylazocarboxylic tert-butyl esters have been achieved
under Barbier-type reaction conditions and in very short reactions times using the …

Palladium‐Catalyzed Sequential C(sp2)‐H Alkynylation/Annulation of 2‐Phenylphenols with Haloalkynes Using Phenolic Hydroxyl as the Traceless Directing Group

G Jiang, S Fang, W Hu, J Li, C Zhu… - … Synthesis & Catalysis, 2018 - Wiley Online Library
Abstract An efficient, palladium (II)‐catalyzed, C (sp2)‐H alkynylation/annulation of 2‐
phenylphenols with haloalkynes for the synthesis of substituted 6‐methylene‐6H‐dibenzo …

[HTML][HTML] SAR: s for the antiparasitic plant metabolite pulchrol. 1. The benzyl alcohol functionality

P Terrazas, E Salamanca, M Dávila, S Manner… - Molecules, 2020 - mdpi.com
Pulchrol (1) is a natural benzochromene isolated from the roots of Bourreria pulchra, shown
to possess potent antiparasitic activity towards both Leishmania and Trypanozoma species …

Zn(II) Chloride Promoted Benzannulation Strategy for One‐Pot Regioselective Synthesis of 6H‐Benzo[c]chromenes

B Muralidhar, SR Reddy - ChemistrySelect, 2017 - Wiley Online Library
A facile highly regioselective Zn (II) chloride promoted protocol for the synthesis of polycyclic
chromene derivatives (6H‐benzo [c] chromenes) is described starting from 4 …

A Garratt-Braverman cyclization route towards the synthesis of phenanthridine derivatives and their DNA-binding studies

A Mandal, P Bhattacharya, AK Das, A Basak - Tetrahedron, 2019 - Elsevier
Garratt-Braverman cyclization has been employed to synthesize a series of dihydroisofuran
fused phenanthridine derivatives. The established protocol proposes a simpler synthetic …