Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review

B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Candida albicans pathogenicity mechanisms

FL Mayer, D Wilson, B Hube - Virulence, 2013 - Taylor & Francis
The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

Candida albicans morphogenesis and host defence: discriminating invasion from colonization

NAR Gow, FL Van De Veerdonk, AJP Brown… - Nature reviews …, 2012 - nature.com
Candida albicans is a common fungal pathogen of humans that colonizes the skin and
mucosal surfaces of most healthy individuals. Until recently, little was known about the …

Candidalysin is a fungal peptide toxin critical for mucosal infection

DL Moyes, D Wilson, JP Richardson, S Mogavero… - Nature, 2016 - nature.com
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate …

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

S Höfs, S Mogavero, B Hube - Journal of microbiology, 2016 - Springer
The interaction between Candida albicans and its host cells is characterized by a complex
interplay between the expression of fungal virulence factors, which results in adherence …

Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review

N Kalia, J Singh, M Kaur - Annals of clinical microbiology and …, 2020 - Springer
Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and
clinical problem but also include large social and psychological consequences …

Candida albicans dimorphism as a therapeutic target

ID Jacobsen, D Wilson, B Wächtler… - Expert review of anti …, 2012 - Taylor & Francis
The ability to switch between yeast and hyphal growth forms (dimorphism) is one of the most
discussed and best investigated virulence attributes of the human pathogenic fungus …

[HTML][HTML] Importance of the Candida albicans cell wall during commensalism and infection

NAR Gow, B Hube - Current opinion in microbiology, 2012 - Elsevier
An imbalance of the normal microbial flora, breakage of epithelial barriers or dysfunction of
the immune system favour the transition of the human pathogenic yeast Candida albicans …

Biofilms and vulvovaginal candidiasis

C Rodríguez-Cerdeira, MC Gregorio… - Colloids and Surfaces B …, 2019 - Elsevier
Candida species, including C. albicans, are part of the mucosal flora of most healthy women,
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …