Phase separation in the outer membrane of Escherichia coli

G Benn, IV Mikheyeva, PG Inns… - Proceedings of the …, 2021 - National Acad Sciences
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with
phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer leaflet. The OM is …

License to Clump: secretory IgA structure–function relationships across scales

A Hockenberry, E Slack… - Annual review of …, 2023 - annualreviews.org
Secretory antibodies are the only component of our adaptive immune system capable of
attacking mucosal pathogens topologically outside of our bodies. All secretory antibody …

Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding

B Schiffrin, JM Machin, TK Karamanos… - Communications …, 2022 - nature.com
Correct folding of outer membrane proteins (OMPs) into the outer membrane of Gram-
negative bacteria depends on delivery of unfolded OMPs to the β-barrel assembly …

A bacterial secretosome for regulated envelope biogenesis and quality control?

DW Watkins, SL Williams, I Collinson - Microbiology, 2022 - microbiologyresearch.org
The Gram-negative bacterial envelope is the first line of defence against environmental
stress and antibiotics. Therefore, its biogenesis is of considerable fundamental interest, as …

The Escherichia coli Outer Membrane β-Barrel Assembly Machinery (BAM) Crosstalks with the Divisome

E Consoli, J Luirink, T Den Blaauwen - International Journal of Molecular …, 2021 - mdpi.com
The BAM is a macromolecular machine responsible for the folding and the insertion of
integral proteins into the outer membrane of diderm Gram-negative bacteria. In Escherichia …

Lpt-protein dynamics reveal that Lipopolysaccharide promotes trans-envelope bridge formation

L Toerk - 2022 - search.proquest.com
Gram-negative bacteria have two lipid bilayers, the inner membrane and the outer
membrane as part of their cell envelope structure. 1 A special feature of the outer layer is its …