[HTML][HTML] Oncological role of HMGA2

S Zhang, Q Mo, X Wang - International journal of …, 2019 - spandidos-publications.com
The high mobility group A2 (HMGA2) protein is a non‑histone architectural transcription
factor that modulates the transcription of several genes by binding to AT‑rich sequences in …

HMGA genes and proteins in development and evolution

R Vignali, S Marracci - International journal of molecular sciences, 2020 - mdpi.com
HMGA (high mobility group A)(HMGA1 and HMGA2) are small non-histone proteins that can
bind DNA and modify chromatin state, thus modulating the accessibility of regulatory factors …

Satellite DNA shapes dictate pericentromere packaging in female meiosis

D Dudka, JM Dawicki-McKenna, X Sun, K Beeravolu… - Nature, 2025 - nature.com
The abundance and sequence of satellite DNA at and around centromeres is evolving
rapidly despite the highly conserved and essential process through which the centromere …

High mobility group a proteins as tumor markers

P Pallante, R Sepe, F Puca, A Fusco - Frontiers in medicine, 2015 - frontiersin.org
Almost 30 years ago, overexpression of HMGA proteins was associated with malignant
phenotype of rat thyroid cells transformed with murine retroviruses. Thereafter, several …

Arctic introgression and chromatin regulation facilitated rapid Qinghai-Tibet Plateau colonization by an avian predator

L Hu, J Long, Y Lin, Z Gu, H Su, X Dong, Z Lin… - Nature …, 2022 - nature.com
Abstract The Qinghai-Tibet Plateau (QTP), possesses a climate as cold as that of the Arctic,
and also presents uniquely low oxygen concentrations and intense ultraviolet (UV) radiation …

High mobility group (HMG) proteins: Modulators of chromatin structure and DNA repair in mammalian cells

R Reeves - DNA repair, 2015 - Elsevier
It has been almost a decade since the last review appeared comparing and contrasting the
influences that the different families of High Mobility Group proteins (HMGA, HMGB and …

HMGA proteins in stemness and differentiation of embryonic and adult stem cells

S Parisi, S Piscitelli, F Passaro, T Russo - International journal of …, 2020 - mdpi.com
HMGA1 and HMGA2 are chromatin architectural proteins that do not have transcriptional
activity per se, but are able to modify chromatin structure by interacting with the …

Identification of genomic regions and candidate genes associated with body weight and body conformation traits in Karachai goats

AA Easa, M Selionova, M Aibazov, T Mamontova… - Genes, 2022 - mdpi.com
The objective of this study was to identify the SNPs and candidate genes related to body
weight and seven body conformation traits at the age of 8 months in the Russian aboriginal …

A single-step genome wide association study on body size traits using imputation-based whole-genome sequence data in Yorkshire pigs

H Liu, H Song, Y Jiang, Y Jiang, F Zhang, Y Liu… - Frontiers in …, 2021 - frontiersin.org
The body shape of a pig is the most direct production index, which can fully reflect the pig's
growth status and is closely related to important economic traits. In this study, a genome …

HMGA2 directly mediates chromatin condensation in association with neuronal fate regulation

N Kuwayama, T Kujirai, Y Kishi, R Hirano… - Nature …, 2023 - nature.com
Identification of factors that regulate chromatin condensation is important for understanding
of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant …