Fostering the unleashing potential of nanocarriers-mediated delivery of ocular therapeutics

D Datta, SP Bandi, V Colaco, N Dhas… - International Journal of …, 2024 - Elsevier
Ocular delivery is the most challenging aspect in the field of pharmaceutical research. The
major hurdle for the controlled delivery of drugs to the eye includes the physiological static …

Advances in ophthalmic therapeutic delivery: A comprehensive overview of present and future directions

A Torkashvand, A Izadian, A Hajrasouliha - Survey of Ophthalmology, 2024 - Elsevier
Ophthalmic treatment demands precision and consistency in delivering therapeutic agents
over extended periods to address many conditions, from common eye disorders to complex …

[HTML][HTML] Nanomedicine: Technologies and Applications

M Farrokhi, F Taheri, M Farrokhi, YEK Tosi… - Kindle, 2024 - preferpub.org
Nanomedicine is an innovative field that merges nanotechnology with medicine, aiming to
enhance diagnosis, treatment, and prevention of diseases at the molecular level. This …

Solid Dispersion Incorporated into Dissolving Microneedles for Improved Antifungal Activity of Amphotericin B: In Vivo Study in a Fungal Keratitis Model

MAS Mahfud, NA Syahirah, M Akram… - Molecular …, 2023 - ACS Publications
Fungal keratitis (FK) is a fungal infection of the cornea, which is part of the eye and causes
corneal ulcers and an increased risk of permanent blindness, which is often found in …

[HTML][HTML] Nanoparticle-based drug delivery systems: An updated strategy for treating fungal keratitis

YX Guo, YX He - Colloid and Interface Science Communications, 2024 - Elsevier
Fungal keratitis is a globally blinding eye disease caused by fungi, with more than 1.05
million cases diagnosed annually, mainly in Asia. It is the most common form of infectious …

Lycium Barbarum Polysaccharide‐Derived Nanoparticles Protect Visual Function by Inhibiting RGC Ferroptosis and Microglial Activation in Retinal Ischemia …

Y Ni, Y Hu, L Zhu, X Jiang, H Zhang… - Advanced Healthcare …, 2024 - Wiley Online Library
Retinal ischemia‒reperfusion (IR) is a major contributor to vision impairment and
irreversible vision loss due to retinal ganglion cell (RGC) injury or loss. Contemporary …

[HTML][HTML] Nano-based drug approaches to proliferative vitreoretinopathy instead of standard vitreoretinal surgery

FS Sorrentino, L Gardini, C Culiersi, L Fontana… - International Journal of …, 2024 - mdpi.com
Proliferative vitreoretinopathy (PVR) has traditionally been managed with vitreoretinal
surgery. Although there have been several recent innovations in this surgery to make the …

Nexus of NFκB/VEGF/MMP9 signaling in diabetic retinopathy-linked dementia: Management by phenolic acid-enabled nanotherapeutics

V Singh, SP Panda - Life Sciences, 2024 - Elsevier
Aims The purpose of this review is to highlight the therapeutic effectiveness of phenolic
acids in slowing the progression of diabetic retinopathy (DR)-linked dementia by addressing …

[HTML][HTML] Drug Delivery Systems for Infectious Eye Diseases: Advancements and Prospects

B Mahaling, N Baruah, A Dinabandhu - Journal of Nanotheranostics, 2024 - mdpi.com
Infectious ocular diseases like keratitis, conjunctivitis, and endophthalmitis pose significant
clinical challenges due to the complexities of delivering drugs to the eye. Recent …

Chondroitin Sulphate-Chitosan Based Nanogels Loaded with Naringenin-β-Cyclodextrin Complex as Potential Tool for the Treatment of Diabetic Retinopathy: A …

G Zucca, B Vigani, C Valentino, M Ruggeri… - International Journal …, 2025 - Taylor & Francis
Purpose The main purpose of the study was the formulation development of nanogels (NHs)
composed of chondroitin sulfate (CS) and low molecular weight chitosan (lCH), loaded with …