The genetics of stress-related disorders: PTSD, depression, and anxiety disorders
JW Smoller - Neuropsychopharmacology, 2016 - nature.com
Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …
factors: genetic vulnerability and environmental stressors. An important role for …
[HTML][HTML] The interplay of hypoxic and mental stress: Implications for anxiety and depressive disorders
J Burtscher, M Niedermeier, K Hüfner… - Neuroscience & …, 2022 - Elsevier
Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …
[HTML][HTML] Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures
The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale
exploration of the links between brain function, behavior, and ultimately genetic variation. To …
exploration of the links between brain function, behavior, and ultimately genetic variation. To …
Biological markers for anxiety disorders, OCD and PTSD–a consensus statement. Part I: neuroimaging and genetics
Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …
are specific to certain disorders or syndromes. The objective of this paper is to summarise …
International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel
Abstract The epithelial Na+ channel (ENaC) and the acid-sensing ion channels (ASICs) form
subfamilies within the ENaC/degenerin family of Na+ channels. ENaC mediates …
subfamilies within the ENaC/degenerin family of Na+ channels. ENaC mediates …
Pharmacology of acid-sensing ion channels–Physiological and therapeutical perspectives
Abstract Development of the pharmacology of Acid-Sensing Ion Channels (ASICs) has
become a key challenge to study their structure, their molecular and cellular functions and …
become a key challenge to study their structure, their molecular and cellular functions and …
[HTML][HTML] Acid-sensing ion channels: focus on physiological and some pathological roles in the brain
Acid-sensing ion channels (ASICs) are Na+-permeable ion channels activated by protons
and predominantly expressed in the nervous system. ASICs act as pH sensors leading to …
and predominantly expressed in the nervous system. ASICs act as pH sensors leading to …
A molecular view of the function and pharmacology of acid-sensing ion channels
S Vullo, S Kellenberger - Pharmacological research, 2020 - Elsevier
The pH in the different tissues and organs of our body is kept within tight limits. Local pH
changes occur, however, temporarily under physiological conditions, as for example in …
changes occur, however, temporarily under physiological conditions, as for example in …
Enhanced harm detection following maternal separation: Transgenerational transmission and reversibility by inhaled amiloride
Early-life adversities are associated with altered defensive responses. Here, we
demonstrate that the repeated cross-fostering (RCF) paradigm of early maternal separation …
demonstrate that the repeated cross-fostering (RCF) paradigm of early maternal separation …
[HTML][HTML] Functional neuroanatomy in panic disorder: Status quo of the research
AIM To provide an overview of the current research in the functional neuroanatomy of panic
disorder. METHODS Panic disorder (PD) is a frequent psychiatric disease. Gorman et al …
disorder. METHODS Panic disorder (PD) is a frequent psychiatric disease. Gorman et al …