OBJECTIVES The aim of this review is to discuss the particularities of coronary artery
disease (CAD), the effect of intensive medical management and the outcome of …

I suggest that insulin suppresses the secretion and antagonizes the harmful effects of tumor
necrosis factor-α, macrophage migration-inhibitory factor, and superoxide anion. Therefore …

Background—The Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction
(DIGAMI) study addressed prognostic factors and the effects of concomitant treatment and …

Objectives: The primary objective of the Monotherapy Assessment of Ranolazine In Stable
Angina (MARISA) trial was to determine the dose-response relationship of ranolazine, a …

Objectives: This study sought to examine whether exenatide is capable of reducing
myocardial infarct size. Background: Exenatide is a glucagon-like peptide (GLP)-1 analogue …

Context Laboratory studies suggest that in the setting of cardiac ischemia, immediate
intravenous glucose-insulin-potassium (GIK) reduces ischemia-related arrhythmias and …

Objectives: This study was designed to determine if the fatty acid-induced increase in H+
production from glycolysis uncoupled from glucose oxidation delays the recovery of …

Background Hyperglycemia is common in critically ill hospitalized patients, and it is
associated with adverse outcomes, including increased mortality. The objective of this meta …

We aimed to assess the clinical efficacy of glucose-insulin-potassium (GIK) in acute
myocardial infarction. Experimental data provided evidence of the beneficial effects of GIK …

After the discovery that glycogen synthase kinase (GSK) 3β plays a fundamental role in the
regulation of the activity of nuclear factor κB, a number of studies have investigated the …